BACKGROUND Oral corticosteroid prescriptions are often used in clinical studies as an indicator of asthma exacerbations. However, there is rarely the ability to link a prescription to its associated diagnosis. The objective of this study was to characterize patterns of oral corticosteroid prescription orders for asthma patients using an electronic health record database, which links each prescr...

background :despite the presence of many textile and dyeing plants in iran, we couldn’t find similar studies in this country. forthermore, considering progress in the dyeing process and engineering controls, assessment of respiratory system is important for these workers. the present study was performed to evaluate the respiratory system in dyeing workers.   methods : in a cross-sectional study...

Acute asthma is a common medical emergency, which, despite repeated review and the publication of international and national guidelines, including the Canadian Asthma Consensus Guidelines, often remains poorly managed. Although there are some signs that evidence-based management of this disorder is improving, a recent survey of the management of asthma in children and adults in the emergency de...

Asthma is a chronic inflammatory disorder of the airways characterized by episodic and reversible symptoms of acute airflow obstruction (narrowing of the airways that makes it difficult to breathe). [1] People with asthma can suffer from symptoms ranging from wheezing, cough and a sensation of tightness in the chest, to a severe inability to expel air from the lungs, suffocation and death. Alth...

Children with acute severe asthma exacerbation are at risk of developing respiratory failure. Moreover, conventional aggressive management might be futile in acute severe asthma requiring intubation and invasive ventilation. The aim of this review is to detail evidence on the use of ketamine in childhood asthma exacerbations. A search of the MEDLINE, EMBASE, and Cochrane databases was performed...

This study was designed to determine the percentage of asthma-related emergency department (ED) visits made by patients who recently ran out of their inhaled short-acting beta-agonists or inhaled corticosteroids and to characterize this understudied patient population. A secondary analysis was performed of data from four ED-based multicenter studies of acute asthma during 1996-1998 (n = 64 EDs)...

BACKGROUND Leukotrienes play a key role in the pathophysiology of chronic asthma. Activation of leukotriene pathways is accompanied by rises in detectable urinary levels of leukotriene E4 (LTE4). The relationship between urinary LTE4 levels and factors associated with acute asthma has not been determined. METHODS Adults aged 15-54 years presenting with moderate to severe acute asthma were eva...

BACKGROUND High sensitivity C-reactive protein (hs-CRP) is an inflammatory marker known to be related to inflammation, infection, and cardiovascular diseases. The aim of this study was to evaluate hs-CRP level in serum of asthmatics and its relationship with pulmonary function tests, serum IgE levels, and peripheral blood white blood cell (WBC) counts. MATERIALS AND METHODS The under study su...

BACKGROUND There is a lack of consensus regarding second-line therapy in children with acute asthma who fail to the standard therapy. Ketamine had bronchodilator property and may be useful in the treatment of acute asthma. OBJECTIVE The objective of this study was to evaluate the efficacy and safety of ketamine as compared to aminophylline in children with acute asthma who respond poorly to t...

BACKGROUND Recent surveys in emergency medicine departments show inadequacies in many aspects of acute asthma management. OBJECTIVE The objective of this study was to evaluate the adherence to management algorithm for acute asthma in the emergency department which focused on evidence-based treatment steps rather than documentation and patient classification. METHODS A retrospective audit of...