In the title compound, C(19)H(19)F(2)NO, the piperidinone ring adopts a chair conformation. The crystal packing is stabilized by C-H⋯O and C-H⋯F inter-molecular inter-actions, generating centrosymmetric dimers of R(2) (2)(14) and R(2) (2)(24) rings.

En este artículo se estudia una escultura de madera a la que atribuimos origen genovés, vinculándola con modelos generados por Antón María Maragliano (1664-1739). Se trata Inmaculada pertenenciente Real Academia Bellas Artes Virgen las Angustias, atribuida antes al escultor Marsella Jean Michel Verdiguier (…1722-1796) y depositada en el Museo Granada desde 1915. Su existencia dicha ciudad es in...

Acute graft-versus-host disease (GVHD). a major complication of allogeneic bone marrow transplantation (BMT). is probably mediated by T lymphocytes present in the marrow graft. In this study. the repopulation of the peripheral blood with T4 and T8 T cells was investigated during the period preceding the occurrence of acute GVHD. Twentyfour allogeneic and 1 1 autologous BMT recipients were monit...

A WebView is a web page automatically created from base data typically stored in a DBMS. Given the multi-tiered architecture behind database-backed web servers, we have the option of materializing a WebView inside the DBMS, at the web server, or not at all, always computing it on the fly (virtual). Since WebViews must be up to date, materialized WebViews are immediately refreshed with every upd...

The CTLA-4 pathway is a key regulator of T cell activation and a critical failsafe against autoimmunity. Although early models postulated that CTLA-4 transduced a negative signal, in vivo evidence suggests that CTLA-4 functions in a cell-extrinsic manner. That multiple cell-intrinsic mechanisms have been attributed to CTLA-4, yet its function in vivo appears to be cell-extrinsic, has been an on...