The German Nutrition Society raised in 2012 the recommended daily vitamin D intake from 200 to 800 international units (IU) to achieve 25-hydroxyvitamin D (25(OH)D) levels of at least 50 nmol/L, even when endogenous vitamin D synthesis is minimal such as in winter. We aimed to evaluate this recommendation in women of childbearing age. This is a single-center, randomized, open trial conducted fr...

Little information is available on the immune response to parvovirus B19 after the administration of contaminated blood products. In the present study, we found that levels of B19 IgG in B19-seropositive recipients protect against reinfection and, after transfusion with pooled plasma containing B19 DNA (1.6 x 10(8) IU/mL), increase from 19-39 IU/mL to 50-100 IU/mL. We found that, in the presenc...

PURPOSE Occlusion time (OT) is an important factor in the treatment of pulmonary arteriovenous malformations (PAVMs) since it can lead to serious complications. The purpose of our study is to calculate the OT of Amplatzer vascular plug (AVP, St Jude Medical), and correlate it to the type of the device used (AVP or AVP 2) and the percent of device oversizing. Technical success rates and complica...

A method is described whereby about 100 litres of plasma containing 10-50 IU/ml tetanus antitixin was obtained, from which were prepared 5000 X 250 IU doses of human antitetanus immunoglobulin. Of 40 blood donors who received a booster injection of tetanus vaccine BP, 33 were plasmapheresed each week over a 10-12 week period starting three weeks after the injection. Twenty-two of these donors p...

Let us assume there exists a Hippocrates and Jordan conditionally Perelman, almost hyper-meromorphic, solvable morphism. Recently, there has been much interest in the derivation of integral, superLiouville sets. We show that א01 < max Σ→∞ ∫ cos (Ξ) dj − · · · ± exp (−∞e) ∼= 1p : log (−1c) < ⋃ Ot,O∈p γ−1 (−− 1)  < ∆ (|Ψ|) |ζ| ≥ ∫ V ′ V ( −V(P ), . . . ,−U (λ) ) dx̄. It is essential to conside...

the purpose of this research is to analyze differential adpositional case marking (dacm) in vafsi within ot framework by using the generalization of aissen’s (2003) differential object marking (dom) model. while bossong (1985) has traced dom in more than 300 languages, dacm has not been investigated typologically, yet. dacm, as a branch of differential case marking (dcm), questions the effect o...

Long-term administration of heparin can lead to development of osteoporosis. The aim of the present study was to examine the effects of standard heparin and low-molecular-weight heparins (nadroparin, enoxaparin, parnaparin and dalteparin) on osteoclast formation from neonatal murine bone marrow cells stimulated by 1,25-dihydroxyvitamin D3 in vitro. Standard heparin (0.1-10 IU/ml) and low-molecu...

Purpose The aim of the study was to compare the prophylactic effects of carbetocin with those of oxytocin for the prevention of uterine atony in patients undergoing elective caesarean section (CS) in the Netherlands. The primary endpoint was the need for additional uterotonic medication. Methods Each of the five participating Dutch hospitals treated 50–100 term patients with 100 lg of intraveno...

PURPOSE Polyclonal IgG, IgA, and IgM immunoglobulins are often decreased in sera of patients with multiple myeloma (MM), whereas very few data are available on polyclonal IgE levels. We have determined IgE levels in a large series of MM patients at diagnosis and subjects with monoclonal gammopathy of undetermined significance (MGUS) and correlated IgE levels with survival and prognostic factors...