BACKGROUND Among individuals without diabetes, elevated hemoglobin A1c (HbA1c) has been associated with increased morbidity and mortality, but the literature is sparse regarding the prognostic importance of low HbA1c. METHODS AND RESULTS National Health and Nutrition Examination Survey III (NHANES III) participants, 20 years and older, were followed up to 12 years (median follow-up, 8.8 years...

Spodoptera frugiperda (Lepidoptera: Noctuidae) is a major pest in maize crops in Colombia, and affects several regions in America. A granulovirus isolated from S. frugiperda (SfGV VG008) has potential as an enhancer of insecticidal activity of previously described nucleopolyhedrovirus from the same insect species (SfMNPV). The SfGV VG008 genome was sequenced and analyzed showing circular double...

Precise localization of the slow atrioventricular nodal pathway (SP) is crucial to safe and successful ablation re-entrant tachycardia (AVNRT). However, interpatient anatomic variability can limit efficacy increase risk for heart block. Activation mapping in sinus rhythm using omnipolar technology (OT) delineate areas abrupt change propagation direction, which may reflect connections between fa...

Gastrointestinal (GI) symptoms are a source of substantial morbidity for people with CF (PwCF), and their assessment treatment present an unmet need. We introduced 3 validated patient reported outcome measures (PROMS) questionnaires investigating GI into routine clinical assessment. evaluated the prevalence severity upper lower in our population. also assessed acceptability using GI-PROMS as to...

OBJECTIVE To test the hypothesis that acute kidney injury (AKI) would be independently associated with increased morbidity and mortality. STUDY DESIGN A total of 96 consecutively cooled infants were reviewed retrospectively. Modified Acute Kidney Injury Network criteria were used to classify AKI based on absolute rise in serum creatinine (SCr) level from a previous trough (stage I, rise in SC...

BIPOLAR disorder is increasingly diagnosed in children and adolescents. Given that antidepressants may precipitate mania, and with increased use of antidepressants in youths, it is reasonable to ask whether antidepressant administration might play a role in inducing earlier manic episodes. We reviewed all consecutive admissions with a diagnosis of bipolar disorder to a university-affiliated chi...