Cells have high-fidelity polymerases whose task is to accurately replicate the genome, and low-fidelity polymerases with specialized functions. Although some of these low-fidelity polymerases are exceptional in their ability to replicate damaged DNA and restore the undamaged sequence, they are error prone on undamaged DNA. In fact, these error-prone polymerases are sometimes used in circumstanc...

TO THE EDITOR—We read with great interest the study by Mylonakis et al that describes a new rapid diagnostic test that detects Candida species directly from blood in 3 hours [1]. The T2 magnetic resonance (T2MR) assay is the first fully automated technology to analyze whole blood specimens in order to identify Candida species without the need for growth from a blood culture. The authors state t...