inflammatory responses and innate immunologic reactions play an important role in the respiratory system. ex vivo lung perfusion (evlp) is considered a novel method in the evaluation and reconditioning of donor lungs prior to transplantation. however, evlp’s effect on inflammatory and metabolic markers of human lung tissue is unknown. this study investigated how the performance of evlp on brain...

background: we evaluated the effect of the ethanolic extract of scrophularia striata on the iranian strain of leishmania major (mrho/ir/75/er) both in vitro and in vivo conditions methods: the effective dose (ed) of ethanolic extract of s. striata were determined using  mtt assay  on the growth of promastigote forms of  l. major in axenic culture media. then, the ed 50 of  s. striata on mice pe...

introduction: urine morphine test, in several countries is the most primarily available qualitative test for detecting opioid abusers. since the users of illicit drugs attempt to defeat urine tests and there are also plenty of claims that usage of hd (high dose) contraceptive pills can result in false-negative results, we decided to design the present study to investigate the probable in vitro ...

the objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (ir) and modified release (mr) tablets. the experiment included rats with both normoglyceamia and streptozocin (stz)-induced hyperglyceamia. several mr formulations were designed and in vitro drug release profile was assessed by a dissolution test. for the fur...