Since the earliest times of history, smallpox left deep traces in memory humanity with great epidemics and destruction (deaths) it caused. Variola virus, which is causative agent smallpox, some other viruses same family have been a part many extraordinary changes field science medicine. Poxviruses privileged position scientific world due to fact that first examples immunization (variolation) an...

The fields of vaccinology and immunology have had a long-standing and complicated relationship. The view that vaccinology is a branch of immunology is more perception than reality. Vaccinology is older, practical, and often idio-syncratic, with its prime focus on the development of functional vaccines that protect a host against a particular microbe. Immunology is younger, conceptual, and striv...