This is a retrospective and comprehensive study of 21 cases of thymoma treated during a period of 30 years (1954-1984). The tumors were staged into 3 categories: stage 1 for encapsulated completely resectable tumor, stage 2 for nonresectable intrathoracic tumor and stage 3 for tumor with extrathoracic spread. According to their lymphocytic content tumors were separated into 3 groups: 1) predomi...

  Although the most common hematological disturbance in thymoma is pure red cell aplasia, pancytopenia is a very rare paraneoplastic syndrome in this disorder. We only found one case in literature reviews. We report a 36 year old female with an anterior mediastinal mass and severe pancytopenia. With a mediastinotomy incision, biopsy of the tumor was obtained. The report of the pathologist was t...

Treatment options for hepatocellular carcinoma have evolved over recent years. Interventional radiologists and surgeons can offer curative treatments for early stage tumours, and locoregional therapies can be provided resulting in longer survival times. Early diagnosis with screening ultrasound is the key. CT and MRI are used to characterize lesions and determine the extent of tumour burden. Im...

introduction: colorectal carcinoma is a main health problem in many countries and the third common cancer in iran. this malignancy at present is the most curable carcinoma of gastrointestinal tract. variation in the expression of the proteins produced by p53, p21, p16, e-cadherin, and β-catenin genes have been noted in this malignancy and may be important in the prognosis and therapeutic respon...

PURPOSE Tumor hypoxia is associated with poor prognosis and increased tumor aggressiveness. Carbonic anhydrase (CA) IX, an endogenous marker for tumor hypoxia, catalyzes the hydration of carbon dioxide into carbonic acid and contributes to the pH regulation of tumor cells. Therefore, CA IX might allow tumors to acclimate to a hypoxic microenvironment, promoting tumor cell proliferation. We hypo...

Introduction: The presence of HER-2 has been shown to be a prognostic factor in many kinds of cancers, but its role in head and neck squamous cell carcinoma (HNSCC) is not still defined. The purpose of the current study is to investigate the role of HER-2 in HNSCC and its correlation with various clinicopathologic parameters.   Materials and Methods: Peripheral blood samples were obtained ...