background :5httlpr polymorphism (5- hydroxytryptamine transporter linked promoter region polymorphism) is the most widely studied genetic variant in psychiatry. the present study is a modest effort at ascertaining the role of 5ht transporter linked promoter region polymorphism (5httlpr) in anxiety and depressive disorders in kashmir (india).the aim of this study was to examine 5-hydroxy trypta...

conclusions the results of the study show no significant association between norepinephrine transporter polymorphism scl6a2 and adhd. results the percentages of adhd subtypes for combined, inattentive, and hyperactive/impulsive were 72.2%, 17.2%, and 11.9%, respectively. there was no significant association between norepinephrine transporter polymorphism and adhd (p = 0.81). moreover, no signif...

Glaucoma is characterized by axonal degeneration of retinal ganglion cells (RGCs) and apoptotic death of their cell bodies, and lowering intraocular pressure is associated with an attenuation of progressive optic nerve damage. Nevertheless, intraocular pressure (IOP) reduction alone was not enough to inhibit the progression of disease, which suggests the contribution of other factors to the gla...

Vehicle Authentication. In recent future, vehicles will establish a spontaneous connection over a wireless radio channel, coordinating actions and information. Vehicles will exchange warning messages over the wireless radio channel through Dedicated Short Range Communication (IEEE 1609) over the Wireless Access in Vehicular Environment (802.11p). Unfortunately, the wireless communication among ...

The pulsatile release of GnRH is crucial for normal reproductive physiology across the life cycle, a process that is regulated by hypothalamic neurotransmitters. GnRH terminals co-express the vesicular glutamate transporter 2 (vGluT2) as a marker of a glutamatergic phenotype. The current study sought to elucidate the relationship between glutamate and GnRH nerve terminals in the median eminence...

Background: Accumulating evidence suggests that the failing heart reprograms fuel metabolism toward increased utilization of ketone bodies and increasing cardiac delivery ameliorates dysfunction. As an initial step development therapies, we investigated effect chronic oral ester (KE) supplementation as a prevention or treatment strategy in rodent failure models. Methods: Two independent models ...

Abstract AIMS • To determine the expression patterns of specific ATP-binding cassette (ABC) transporters in medulloblastoma assess whether ABC play a role acquired drug resistance SHH using drug-tolerant cell line models extracellular vesicles transfer drug-tolerance and mechanism by which they do this METHOD Drug-tolerant lines were generated continuous culture drug-containing medium. trans- p...

introduction: prolonged and intermittent oxygen pre-exposure is associated with protection against ischemic reperfusion (ir) injury. in the current study, attempts were made to investigate the relationship between exposure to prolonged and intermittent normobaric hyperoxia (nbho) and expression of excitatory amino acids transporters (eaats) and tnf-α level. method: rats were divided into four m...