In the mature eye, three distinct tissue fates, retina, ciliary body, and iris, arrange with a strict linear organization along the central (back) to peripheral (front) axis. The establishment of this topographical relationship within the optic vesicle is not well understood. We use a targeted vital labeling strategy to test the derivation of mature eye tissues from the optic vesicle of the chi...

ABSTRACT The presence of neurofibrillary tangles in the brain is a hallmark feature of several neurodegenerative diseases termed "tauopathies," including Alzheimer's disease (AD) and the tau molecular subgroup of frontotemporal lobar degeneration (FTLD-tau). Recently, several positron emission tomography (PET) radiopharmaceuticals targeting abnormal conformations of the tau protein have been de...

Abstract Dust storms may remarkably degrade the imaging quality of Martian orbiters and delay progress mapping global topography geomorphology. To address this issue, paper presents an approach that reuses image dehazing knowledge obtained on Earth to resolve dust-removal problem Mars. In approach, we collect remote-sensing images captured by Tianwen-1 manually select hundreds clean dusty image...

The production of geological mapping by conventional processes is a complex work of data gathering and integration, along with expert and team analysis. This process is very time consuming, since it implies several expeditions to the study location. In the organization studied by this paper, this process can take several years to be completed. The objective of this project is to build a remote ...

Nanopipettes are becoming extremely versatile and powerful tools in nanoscience for a wide variety of applications from imaging to nanoscale sensing. Herein, the capabilities of nanopipettes to build complex free-standing three-dimensional (3D) nanostructures are demonstrated using a simple double-barrel nanopipette device. Electrochemical control of ionic fluxes enables highly localized delive...

3-D flash ladar, herein defined as obtaining an entire frame of 3-D ladar data with one laser pulse, is an emerging technology with a number of advantages over conventional point scanner systems. Probably the most obvious advantage is the higher data rates possible and the potential for much higher data rates with increases in the associated 3-D focal planes array (FPA) format. High data rate m...

Affective states might influence inhibitory control, a cognitive process fundamental for goal adaptive behavior. Here, we recorded high-density EEG while participants performed an antisaccade task, after the induction of a happy (n=20) or neutral (n=20) mood, to compare the same inhibition-related processes across these two affective contexts. Topographical evoked potential mapping methods were...