A case of dietary amenorrhoea associated with the biochemical picture of subclinical hypothyroidism is described. Both the amenorrhoea and the abnormal thyroid function tests reverted to normal on gaining weight.

Clinicians experience difficulty in correctly interpreting the results of in vitro thyroid function tests in the presence of abnormalities of thyrobinding proteins or when results are borderline. This difficulty has been largely resolved in our laboratory by three innovations. First, the borderline areas for each of three routine tests of thyroid function (total thyroxine, thyrobinding index, a...

Children with Down syndrome are at a higher risk of thyroid dysfunction than children in the general population. The aim of this audit was to determine thyroid screening practice at University Hospital Limerick and to compare it to the Irish guidelines for the medical management of children with Down syndrome. The thyroid function tests (TFT) of 148 children with Down syndrome were assessed thr...