Background/Aim: Hemodynamic variations are inevitable during induction of anesthetic drugs. The present study, investigates the hemodynamic variations of two different drugs used for induction; Thiopental vs. Propofol. Materials and Methods: In a prospective randomized double-blind study, from June 2003 to November 2004, 120 (ASA I and II) patients scheduled for elective surgery, were randomly ...

OBJECTIVE The aim of this study was to retrospectively evaluate the intensive care unit treatments applied to obstetrics patients with a diagnosis of posterior reversible encephalopathy syndrome (PRES). MATERIAL AND METHODS The cases of 7 pregnant patients who had been diagnosed with PRES between July 2011 and July 2013 were retrospectively reviewed. The patients' clinical data, brain magneti...

BACKGROUND Microglial cells play important roles in coordinating the inflammatory brain responses to hypoxia and trauma. Ionotropic P2X receptors and metabotropic P2Y receptors (P2YRs) expressed in microglia can be activated by extracellular adenosine triphosphate (ATP) derived from damaged cells or astrocytes, and participate in the signaling pathways evoked in brain insult. Although several i...

their optimal clinical utilization. History and Principles Whereas inhaled anesthetics are useful for the induction of anesthesia, particularly in the absence of IV access as occurs commonly in pediatric anesthesia, IV anesthetics have become the primary agents for the induction of general anesthesia. The development of IV anesthetics followed the late 19th-century introduction of hollow needle...

The use of propofol as an induction agent for surgeries lasting less than 2 hours has been shown to result in a faster emergence from anesthesia. Our study was performed to analyze the impact of propofol on surgical procedures lasting longer than 2 hours. A convenience sample of 84 men and women undergoing nonemergency laparoscopic procedures scheduled for longer than 2 hours were enrolled in t...

To determine if clinical concentrations of halothane have direct relaxant effects on airway smooth muscle, the authors compared dose-response curves to histamine in the control state (thiopental) and during halothane anesthesia (1.0 and 1.5 MAC), in six basenji-greyhound (BG) dogs untreated and pretreated with atropine aerosols (10 mg X ml-1). Pulmonary resistance (RL) and dynamic compliance (C...

In this double-blind, placebo-controlled study, we examined the effects of subanaesthetic doses of ketamine (an NMDA glutamate receptor antagonist) and thiopental (a GABA-A receptor agonist) on the event-related potential (ERP) correlates of deviant stimulus processing in 24 healthy adults. Participants completed three separate pharmacological challenge sessions (ketamine, thiopental, saline) i...

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