Marijuana (Cannabis sativa) and its primary psychoactive component, delta-9-tetrahydrocannabinol (Delta(9)-THC), have long been known to disrupt cognition in humans. Although Delta(9)-THC and other cannabinoids disrupt performance in a wide range of animal models of learning and memory, few studies have investigated the effects of smoked marijuana in these paradigms. Moreover, in preclinical st...

The relationship between reaction time and visual latcncy rclative to a fixed stimulus has been measured in haploscopic vision by means of the flicker effect produced by two stimuli of different luminance levels. The fields of foveal vision wcrc of 5 0 , thc retinal illuminance was from 8 to 110 td and three obscrvcrs wcrc used. The results show in all cases that the motor componcnt in ...

Shifting policies towards legalisation of cannabis for therapeutic and recreational use raise significant ethical issues for health-care providers seeking evidence-based recommendations. We investigated whether heavy cannabis use is associated with persistent harms to the hippocampus, if exposure to cannabidiol offers protection, and whether recovery occurs with abstinence. To do this, we asses...

A preliminary field evaluation of a second-generation handheld oral fluid testing device, the Alere DDS2 Mobile Test System (DDS2), is described. As part of a larger study, drivers were randomly stopped at various locations across California (in 2012) and asked to submit voluntarily to a questionnaire regarding their drug and alcohol use, a breath alcohol test and collection of oral fluid with ...

Ten experienced licensed private pilots were trained for 8 hours on a flight simulator landing task. They each smoked a cigarette containing 19 mg of delta 9-tetrahydrocannabinol (THC), and 24 hours later their mean performance on the flight task showed trends toward impairment on all variables, with significant impairment in number and size of aileron changes, size of elevator changes, distanc...

Rongqing Chen,1,4 Jian Zhang,1,4 Ni Fan,1,4 Zhao-qian Teng,1,4 Yan Wu,1,4 Hongwei Yang,1 Ya-ping Tang,3 Hao Sun,1 Yunping Song,1 and Chu Chen1,2,* 1Neuroscience Center of Excellence 2Department of Otorhinolaryngology 3Department of Cell Biology and Anatomy School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA 4These authors contributed equally to this...

Thc SEC developcd this statcment 1)1' revicwing kCI' educllional and historical documcl1ls of AOTA. A draft of this papel' was distributcd bmadly for review ancl commel1l to kel' constitucl1l groups ancl leadcrs of the Associarion, Two cycles of review were completed before the statement Ivas submitted to the Representarive Assembly in 1993. The intent of the statement is nor to delineate all p...

The Hedlcy area is situated approximately 40 kilometrcs castsllutlieast ufPrinceton. ill southwestern Br1tis.h Columbia. 'She main objectives of this thrcc-year project. ujhich war initiated in 1985, include: (a) To geologically mqJ. at a scale of I:20 0 0 0 , the Hedley area. (bj To exarninc the gecNchemistry, controls. and rcgiondl setting of the numerous golc dcposits in the Hcdley district,...

A basic concept in stochasti~ test theory is the item aharaateristia aurve fi(t )' Let t be an individual parameter represcntv v ing e.g. the ability of an individual v in an achievement test 01' thc aggressiveness of the individual in an aggressivity test. Thon we introduce a randem variable a . such that a . = 1 if VI VI the individual v gives a positive ("correct", "aggressive") response to ...