Confluent and Reticulate Papillomatosis (CRP) is a rare disease withpoorly recognized etiology. Various agents such as antibacterial,topical/systemic antifungal and topical/oral retinoids have beenused as treatment. Here, we report a 15-year-old female withCRP in whom yeasts of Malassezia were found in the PAS stainof the skin lesions. Topical terbinafine hydrochloride 1% sprayand oral fluconaz...

The prevalence of drug resistance has become an important issue in various yeast infections, which have a significant effects on both human animal health. In this study, an attempt has been made to determine susceptibility pattern of two antifungal agents Terbinafine and Ketoconazole against 45 oral and non oral Candida albicans isolates using broth microdilution method. Under in vitro conditio...

Erratum for Mirhendi et al., the first case of onychomycosis in a koala (phascolarctos cinereus) due to atypical isolates of Microsporum gypseum, a diagnostic challenge Mirhendi H1,2*, Nishiyama Y3, Rezaei-Matehkolaei A4, Satoh K5, Makimura K5 1. Department of Medical Parasitology & Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 2. Department of Medi...

Due to the increase of choices relative to antifungals, there is a need to improve the standardization of in vitro methods used to determine the antifungal susceptibility of fungal pathogens. Our study evaluated the in vitro susceptibility of filamentous fungi isolated from patients with toenail onychomycosis against itraconazole, ciclopirox, eberconazole, fluconazole and terbinafine. The minim...

Combination therapy is one way of improving the cure rate of onychomycosis. The LION Study examined the efficacies of terbinafine and itraconazole. The Icelandic cohort of the study reported that after 5 years only 46% of the terbinafine-treated patients and 13% of the itraconazole-treated patients were still disease-free, suggesting that relapses and reinfections were common in the long term t...

Subacute cutaneous lupus erythematosus (SCLE) is a well-defined subtype of lupus erythematosus, characterised by photosensitivity, annular and/or psoriasiform lesions, variable systemic involvement and presence of circulating SSA/anti-Ro antibodies. SCLE may be idiopathic or drug-induced. Both the idiopathic and drug-induced forms of SCLE are analogous in their clinical, serological and histolo...

Tinea capitis (TC) is a common childhood fungal infection which, if untreated, can cause long-term scarring. A number of antifungal drugs with proven efficacy are available for the treatment of TC. However, varying dosage schedules, changes in epidemiology, and rising drug resistance are factors that hamper treatment in some cases. A prospective, non-blinded, cross-sectional study of three comm...

OBJECTIVE To identify and synthesize the evidence for the efficacy of oral treatments for fungal infections of the toenails. DESIGN Systematic review of randomized controlled trials. INTERVENTIONS Oral treatments for dermatophyte infections of the toenails. MAIN OUTCOME MEASURES Cure confirmed by microscopy and culture results in patients with clinically diagnosed fungal infections. Data ...

OBJECTIVE This open randomized study examined the efficacy of a combination of oral terbinafine and topical amorolfine in the treatment of severe dermatophyte toenail onychomycosis with matrix area involvement. PATIENTS/METHODS A total of 147 patients were randomized to one of three treatment groups: 15 months of once-weekly topical amorolfine lacquer in combination with 6 weeks (Group AT6) o...