The existence of multiple molecular weight forms of DNA polymerase in different cellular locations of eukaryotie cells, and the demonstration that these enzyme activities have quite different properties (l-4) raise a number of questions about DNA metabolism in complex organisms. Some of these questions were implicit in the early work on mammalian DNA polymerase; particularly the demonstration t...

In addition to their well-known preference for sugars, mice and rats avidly consume starch-derived glucose polymers (e.g., Polycose). T1R3 is a component of the mammalian sweet taste receptor that mediates the preference for sugars and artificial sweeteners in mammals. We examined the role of the T1R3 receptor in the ingestive response of mice to Polycose and sucrose. In 60-s two-bottle tests, ...

any studies have demonstrated that the use of chewing gum stimulates salivary flow, thus, enhancing the saliva remineralization potential. Fructooligosaccharides (FOS) are used in some countries as sucrose substitutes, but their cariogenic potential has not been completely elucidated yet. The aim of this study was to evaluate the effect of chewing gum containing sucrose or FOS (Meiji Seika, Jap...

The identity, localization and physiological significance of enzymes involved in sugar uptake and accumulation were determined for endocarp tissue of pods of Kentucky Wonder pole beans (Phaseolus vulgaris). An intracellular, alkaline invertase (pH optimum, 8) was assayed in extracted protein, as well as enzymes involved in sucrose synthesis, namely, uridinediphosphate (UDP-glucose pyrophosphory...

A sucrose-rich diet has repeatedly been observed to have cocarcinogenic actions in the colon and liver of rats and to increase the number of aberrant crypt foci in rat colon. To investigate whether sucrose-rich diets might directly increase the genotoxic response in the rat colon or liver, we have added sucrose to the diet of Big Blue rats, a strain of Fischer rats carrying 40 copies of the lam...

The recent article by Montonen et al. (1) fails to demonstrate that a higher intake of fructose, glucose, and sweetened beverages (but not sucrose) may increase type 2 diabetes risk because 1) the authors do not acknowledge the fundamental compositional and metabolic similarities between monosaccharide (fructose 1 glucose) and disaccharide sucrose, and 2) their conclusion regarding diabetes ris...

Consumers' awareness about the nutritional profile of their diets has made the industry to respond their needs seriously. In this study, response surface methodology was used to analyze the effect of three fat replacers and two sweeteners on sensory attributes and viscosity of low- calorie pistachio butter. Balangu seed extract (BSG) (0.01-0.04), Reihan seed gum (RSG) (0.01-0.023), xanthan (0.0...

James, W. P. T. (1972). Archives of Disease in Childhood, 47, 531. Comparison of three methods used in assessment of carbohydrate absorption in malnourished children. The results of oral lactose and sucrose tolerance tests were compared with jejunal disaccharidase activities and the absorption rates of lactose and sucrose from a perfused segment of jejunum in 8 malnourished children before and ...

Background: Epididymal spermatozoa have been used for production of offspring from genetically important animals after they are dead. To attain optimal fertility with epididymal spermatozoa, they should be preserved in a suitable medium in 37°C. Preservation media provides requirement for spermatozoa and affects its motility, viability, and fertility. Sucrose is one of the important components ...