نتایج جستجو برای: sporadic
تعداد نتایج: 21803 فیلتر نتایج به سال:
BACKGROUND Medullary thyroid carcinoma (MTC) may occur either as sporadic or as hereditary. Even though the sporadic form corresponds to the majority of cases, the pathogenesis is still unclear. Several polymorphisms of the ret proto-oncogene, including those located in exon 11, 13, 14 and 15 have been described in the general population and some of them seem to be over-represented in sporadic ...
Введение. Спорадическая ретинобластома развивается в результате мутаций de novo обоих аллелях гена RB1 клетках сетчатки глаза. При спорадической ретинобластоме первоначальная мутация гене нередко является мозаичной, то есть образуется постзиготической ранней эмбриональной клетке, что приводит к неравномерному распределению мутантных клонов между различными тканями организма. Возможность идентиф...
Gastrinomas and insulinomas are frequent in multiple endocrine neoplasia type 1 (MEN1). The MEN1 tumor suppressor gene was recently identified. To elucidate the etiological role of the MEN1 gene in sporadic enteropancreatic endocrine tumorigenesis, we analyzed tumors (28 gastrinomas and 12 insulinomas) from 40 patients for MEN1 gene mutations and allelic deletions. One copy of the MEN1 gene was...
Amniotic Band Syndrome is a sporadic congenital disorder that may result in constriction bands, amputation and multiple craniofacial, visceral and body wall defects. Its incidence is estimated at approximately 1:5000 to 1:10,000 pregnancies. Band formation most frequently affects the distal segments, including the hand. We report a case of constriction amniotic bands involving the trunk.
We prove two-term supercongruences for generalizations of recently discovered sporadic sequences of Cooper. We also discuss recent progress and future directions concerning other types of supercongruences.
Sporadic colobomata may be associated with a variety of secondary changes, and these have been classified and discussed with special reference to unusual findings published during recent years. Clinically some cases may appear to be neoplastic, and pathological examination may be important in demonstrating their true nature. A malformation apparently not previously reported is described.
EDITORIALS 401 live” dosage of irradiation therapy. About 50 percent of these patients achieve good palliation of their disease for periods of a few months to over one year. Those with no demonstrable spread of tumor beyond the confines of the esophagus are taken directly to surgery, where esophagogastrostomy is our preferred operative procedure. Patients who have localized extension of tumor b...
This is an introduction to finite simple groups, in particular sporadic groups, intended for physicists. After a short review of group theory, we enumerate the 1 + 1 + 16 = 18 families of finite simple groups, as an introduction to the sporadic groups. These are described next, in three levels of increasing complexity, plus the six isolated “pariah” groups. The (old) five Mathieu groups make up...
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