The subgroup J of avian leukosis virus causes myelocytomas, a neoplastic condition the birds that affects several visceral organs. In present study, myelocytomas were diagnosed in adult laying based on cytological and histopathological examination. On necropsy examination, showed enlarged liver spleen with multifocal tumorous growths liver, spleen, kidneys, lungs, ovary, proventriculus, intesti...

This study evaluates ameliorative effect of Pleurotus tuberregium on the effects lead (Pb) using different concentrations /growers mash feed mixture in 90 Albino rats divided into six groups with three replicates (with 5 per group) for 21days pre-experimental stage proper acclimatization. There after all experimental were exposed to 0.1 g/l daily 21days. At end exposure period, salt was discont...

The spleen gets no respect. Long seen as superfluous, the adult spleen of the mouse has recently been shown to hold stem cells that, in diabetic mice or genetically altered mice that lack a pancreas, effectively regenerate insulin-producing islet cells of the pancreas. Stem cells of the spleen express Hox11, a highly conserved transcription factor that plays a major role in the development of o...

A method is described for the detection of interferon production by individual spleen cells of mice after intravenous virus infection. Although mouse spleen plays a major role in the total interferon response to Newcastle disease virus, the number of spleen cells participating is a small fraction of the total, suggesting that interferon formation is to some extent a specialized cell function. M...

Regulatory effects of alloantigen-activated thymus-derived lymphocytes in mixed lymphocyte reactions have been demonstrated. Mice were injected into foot pads with allogeneic spleen cells; 4 days following sensitization spleen or regional lymph node cells from these animals were treated with mitomycin C and incorporated into MLR as regulator populations syngeneic to the responder cell type. Act...

With the exception of lymphoma involving the spleen, other primary and secondary neoplasms are rare and infrequently encountered. Primary malignant neoplasms involving the spleen are lymphoma and angiosarcoma. Primary benign neoplasms involving the spleen include hemangioma, lymphangioma, littoral cell angioma and splenic cyst and solid lesions such as hamartoma and inflammatory pseudotumor.

An intravenous immunizing infection with the facultative, intracellular parasite, Listeria monocytogenes results in the production in the spleen of a population of immunologically-committed lymphocytes which can adoptively immunize normal recipients against a lethal challenge infection. These cellular mediators of immunity are first produced in the spleen between days 2 and 4 of infection and r...

Lectin agglutination and cell surface galactosyltransferase (EC 2.4.1.67; 1-O-alpha-D-galactosyl-myo-inositol:raffinose galactosyltransferase) enzyme activity have been studied with thymus and spleen lymphocytes of neonatal rats. Thymus lymphocytes were more agglutinable by concanavalin A than by wheat germ agglutinin, whereas spleen lymphocytes were more agglutinable by wheat germ agglutinin t...

Spleen and bone marrow cells from DBA/2 mice protected against infection with a leukemogenic dose of Friend leukemia virus (FLV) by passive therapy with chimpanzee anti-FLV serum were shown to be able to adoptively transfer antiviral resistance to unimmunized irradiated syngeneic recipients. Similar to the results obtained with donor mice immunized against a synge neic FLV erythroleukemia cell ...