Effects of leukotriene (LT) C4 and LTD4 on coronary artery spasm in atherosclerotic miniature pigs were examined angiographically. Endothelial balloon denudation of the left circumflex coronary artery was performed in 15 Gottingen miniature pigs; 11 were fed a 2% cholesterol diet and four were fed a regular diet for 3 months. Three months after this denudation, the area of the coronary artery w...

Introduction Recently, pulmonary vein isolation (PVI) with cryoballoon (CB) has been widely accepted as treatment for atrial fibrillation (AF). Especially, second-generation CB (Arctic Front Advance, Medtronic, Inc, Minneapolis, MN) has a high cooling effect, which can achieve durable lesions of pulmonary vein (PV) antrum and better clinical outcomes. On the other hand, several complications, s...

The carotid angiograms of 96 patients who had died from non-missile head injury were reviewed and assessed for evidence of arterial spasm, slowing of the cerebral circulation, and the presence of intracranial haemotoma. As bilateral angiography had been done in 44 cases the results are based on a correlation between the angiographic appearances and the presence or absence of ischaemic brain dam...

A Model for Experimental Cerebral A rterial Spasm • Vasospasm of the basilar artery of the dog was induced by subarachnoid injection of arterial blood through the cisterna magna. Cerebral angiography was employed to evaluate quantitative assessment of the spasm. Chronic vasospasm was successfully induced in 100% of surviving dogs. Biphasic vasoconstriction was observed. The acute phase occurred...

3 Silverman ME, Flamm MD: Variant angina pectoris-Anatomic &ding and pmgno8tic implications. Ann Intern Med 75:339,1971 4 Prinzmetal M, K m e r R, Merliss R, et al: Angina pedwis I. Variant form of angina pectoris. Am J Med 27:375, 1959 5 Hart NJ, Silverman ME, King SB: Variant angina pedwis caused by coronary artery spasm. Am J Med 356:e69, 1974 6 Oliva PB, Potts DE, Pluss RC: Coronary arteria...

Coronary artery vasospasm following administration of sublingual (SL) nitroglycerin (NTG) was first described in the literature by Feldman and colleagues in 1978 [1]. The frequency of this finding and its clinical significance is unknown; however, it is corroborated by other reports of paradoxical blood pressure elevation after nitroglycerin administration [2] and anecdotally noted rare patient...

Background. It has been suggested that recurring coronary artery spasm may lead to the development of fixed atherosclerotic coronary obstructions. Methods and Results. We studied 10 patients with typical Prinzmetal's variant angina in whom the disease remained active for years and in whom occlusive coronary spasm occurred reproducibly at the same arterial site during repeat coronary arteriograp...

BACKGROUND Coronary artery spasm (CAS) is defined as a reversible, sudden epicardial coronary artery stenosis that causes vessel occlusion or near occlusion. CASE REPORT In this article, we present a clinical case of CAS in a 48-year-old woman undergoing elective aortic valve replacement surgery for aortic stenosis. On the 3rd post-operative day, the patient suffered from chest pain and dyspn...