For skin contact medical devices, realizing a strong with is essential to precisely detect human biological information and enable human-machine interaction. In this study, we aimed fabricate characterize an inclusion complex film (ICF) for adhesion using α-cyclodextrin (α-CD) nonanyl group-modified PVA (C9-PVA) under wet conditions. Based on the water insolubility of C9-PVA ability α-CD alkyl ...

The simultaneous application of ultrasound and the surfactant sodium lauryl sulfate (referred to as US/SLS) to skin enhances transdermal drug delivery (TDD) in a synergistic mechanical and chemical manner. Since full-thickness skin (FTS) and split-thickness skin (STS) differ in mechanical strength, US/SLS treatment may have different effects on their transdermal transport pathways. Therefore, w...

INTRODUCTION The management of sensitive skin, which affects over 60% of the general population, has been a long-standing challenge for both patients and clinicians. Because defective epidermal permeability barrier is one of the clinical features of sensitive skin, barrier-enhancing products could be an optimal regimen for sensitive skin. In the present study, we evaluated the efficacy and safe...

The simultaneous application of ultrasound and the surfactant sodium lauryl sulfate (referred to as US/SLS) to skin enhances transdermal drug delivery (TDD) in a synergistic mechanical and chemical manner. Since full-thickness skin (FTS) and split-thickness skin (STS) differ in mechanical strength, US/SLS treatment may have different effects on their transdermal transport pathways. Therefore, w...

BACKGROUND Literature data indicate that terrestrial life stages of amphibians may be more sensitive to xenobiotics than birds or mammals. It is hypothesized that dermal exposure could potentially be a significant route of exposure for amphibians, as there is evidence that their skin is more permeable than the skin of other vertebrate species. Thus, higher amounts of xenobiotics might enter sys...

A review of field production data reveals that usually, it is very difficult to apply available decline models because of poor quality and often noisy character of initial data and also unrealistic assumptions of the models. This paper tries to introduce applicable procedures to correct initial data and reproduce missed data. Corrected data are analyzed and finally, the results for permeability...

Abstract Literature solubilities have been used to obtain properties or descriptors of melatonin. These indicate the chemical nature melatonin: it is dipolar and has moderate hydrogen bond acidity basicity. The can be combined with equations that we previously constructed estimate water–solvent partition coefficients in a huge number organic solvents. In same way, range biological estimated. in...

conclusions the results indicated that sod-loaded in sln was delivered into deep burned skin layer and induced high enzyme activity through the skin. low particle size, application of lecithin as surfactant and low crystallinity index (ci) percentage were important factors for increasing sod penetration through the burned rat skin. percentage of activity by sln dispersions through rat skin was ...