نتایج جستجو برای: receptor pharmacology

تعداد نتایج: 615995  

Journal: :Expert opinion on therapeutic patents 2012
Rose M Santangelo Timothy M Acker Sommer S Zimmerman Brooke M Katzman Katie L Strong Stephen F Traynelis Dennis C Liotta

INTRODUCTION The NMDA receptor is a ligand-gated ion channel that plays a critical role in higher level brain processes and has been implicated in a range of neurological and psychiatric conditions. Although initial studies for the use of NMDA receptor antagonists in neuroprotection were unsuccessful, more recently, NMDA receptor antagonists have shown clinical promise in other indications such...

2008
Iwan de Esch Rob Leurs

Dr. Iwan de Esch is an assistant professor and Prof. Rob Leurs is full professor and head of the Division of Medicinal Chemistry of the Leiden/Amsterdam Center of Drug Research (LACDR), VU University Amsterdam, The Netherlands. Since the seventies, histamine receptor research has been one of the traditional themes of the division. Molecular understanding of ligand-receptor interaction is obtain...

Journal: :Epilepsy currents 2013
Gregory L Krauss

Perampanel is a selective, noncompetitive AMPA receptor antagonist that has recently been approved for treating localization-related epilepsy. This article reviews the pharmacology, clinical development, efficacy, and safety/tolerability of perampanel.

Journal: :The Journal of pharmacology and experimental therapeutics 2003
Magnus M Berglund Douglas A Schober Michail A Esterman Donald R Gehlert

The pancreatic polypeptide-fold family of peptides consists of three 36-amino acid peptides, namely neuropeptide Y (NPY), peptide YY, and pancreatic polypeptide (PP). These peptides regulate important functions, including food intake, circadian rhythms, mood, blood pressure, intestinal secretion, and gut motility, through four receptors: Y1, Y2, Y4, and Y5. Additional receptor subtypes have bee...

Bahramnezhad, Fatemeh, Chegini, Najmeh,

Introduction: The majority of nursing students believed that their knowledge in the field of pharmacology is far from the desired level, which can be due to the large volume of intensive one-semester content and ineffective teaching of the pharmacology course. Accordingly, this study has determined and compared education with the mobile application and puzzle classroom on memorization of pharma...

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