provide a complete document that would be applicable to the case management of diarrhea. However, some explanation and amplification is necessary to clarify the terms and phrases that have been used, as well as to explain the basis for certain decision pathways in the algorithm. Adult: The definition of 'adult' varies from one country to another. As applied in this guideline, the term 'adult' r...

3552 Background: Capecitabine has the potential to replace 5-FU as standard agent in combination with radiotherapy in rectal cancer. Cetuximab is a monoclonal antibody directed against the epidermal growth factor receptor. Both agents are active in the treatment of colorectal cancer and have demonstrated radiosensitising properties. The aim of this study was to assess the feasibility of combini...

Prostatic mesenchymal tumours are extremely uncommon benign tumors and very few cases have been published. Our case presented with diarrhea increased urinary frequency normal serum PSA levels. On multi-parametric MRI diffusely enlarging prostate loss of zonal anatomy possibility inflammatory etiology was suggested. Trus guided biopsies were reviewed, which followed by immunohistochemistry aided...

BACKGROUND/AIMS Concurrent chemoradiotherapy (CCRT) is considered the treatment option for locally advanced pancreatic cancer, but accompanying gastrointestinal toxicities are the most common complication. With the introduction of three-dimensional conformal radiotherapy (3-D CRT) and intensity-modulated radiotherapy (IMRT), CCRT-related adverse events are expected to diminish. Here, we evaluat...

With the aim of setting up an animal model of Shigella dysenteriae-induced diarrhea, Wistar rats received per os increasing densities of S. dysenteriae type 1 (Sd1). Inoculum of 12 x 10(8) Sd1 provoked dysenteric diarrhea within 24 h. Feces of healthy rats were molded, brown to black and rough. Rats developing diarrhea presented blood at the anal orifice; stools were soft or liquid containing m...

AIMS AND BACKGROUND Adjuvant external beam radiotherapy is highly recommended for uterine carcinomas invading beyond the inner half of the myometrium or cervical stage IIa carcinomas. The addition of a booster intracavitary dose is widely used. METHODS We assessed the feasibility and toxicity of a hypofractionated accelerated conformal radiotherapy scheme (2.7 Gy per fraction, for 14 consecut...

Objective(s): This study was designed to investigate various gastrointestinal effects of Manilkara zapota (Sapodilla), exploring its anti-diarrheal, anti-secretary, anti-spasmodic, anti-ulcer and anti-motility potential.Materials and Methods: Antidiarrheal and anti-secretary activities were investigated using castor oil induced diarrhea ...

Introduction: Ionizing radiation is non-surgical treatment of brain tumors and metastases. Preclinical studies have showed main insights into harmful effects of radiation on the nervous system in vivo and in vitro. Cognitive impairment such as progressive memory, executive and attention performance deficits indicates a significant risk for patients experiencing conventional rad...