In 1990-2002, the authors conducted a population-based cohort study of 2,447 Caucasian men in Olmsted County, Minnesota, to determine whether daily users of nonsteroidal antiinflammatory drugs (NSAIDs) were at lower risk than nondaily NSAID users of developing benign prostatic hyperplasia. Participants completed validated questionnaires during a home visit, including information about daily NSA...

Here, we report a case of stromal tumor of uncertain malignant potential (STUMP) that was difficult to diagnose. A 53-year-old male was found to have a hard nodule on digital rectal examination; magnetic resonance imaging revealed a large nodule on the left side of the prostate, indicating prostate cancer. However, pathological diagnosis of the biopsy specimen was benign prostatic hyperplasia. ...

PURPOSE To determine the probability of having prostate cancer (PCa) using the combination of serum level of prostate-specific antigen (PSA) and age. MATERIALS AND METHODS A total of 160 patients and 190 controls were enrolled in this hospital-based case-control study. Using a logistic regression model and the odds ratio of age and PSA level, the probability of PCa was estimated based on seru...

OBJECTIVES To compare the effects and histopathological changes of botulinum neurotoxin type A and lysozyme gene injections into prostate tissue within a testosterone induced benign prostate hyperplasia rat model. MATERIALS AND METHODS 40 male Wistar rats were randomized into four Groups. Group-1: Control, Group-2: Testosterone replacement, Group-3: Testosterone+botulinum neurotoxin type A, G...

...................................................................................................... 1 TABLE OF CONTENTS................................................................................. 2 ORIGINAL PAPERS ....................................................................................... 4 LIST OF ABBREVIATIONS...................................................................

Genitourinary tuberculosis accounts for approximately 5.3% of extrapulmonary [1]. It may involve the kidneys, ureters, bladder, prostate, vas deferens, epididymis, and testes. However, prostatic can exceptionally be found as an isolated lesion. We report a case 60-year-old patient who was admitted to emergency room with Acute urinary retention, treated benign hyperplasia, failure medical treatm...

Prostate cancer is the second most commonly diagnosed malignancy in men worldwide. The prevalence has been increasing with significant differences between regions. This study assesses of incidental prostate detected specimens removed during bladder outlet obstruction operation. A retrospective analysis records patients who had either endoscopic or open prostatectomy from January 1998 to Decembe...

Role of prolactin in the prostate gland – Studies in transgenic models Jon Kindblom Department of Physiology, The Sahlgrenska Academy, Göteborg University, Sweden The aim of the studies in this thesis was to investigate the role of prolactin (PRL) in normal and pathophysiological conditions of the prostate gland using three different genetically modified mouse models. Benign and malignant disor...

Background: Benign prostatic hyperplasia (BPH) is the most common benign tumor in men. The etiology of BPH is still unresolved and multiple systems are likely to be involved. The effects of diabetes on urinary system are a risk factor for BPH. We then assessed the effects of diabetes on the parameters related to BPH, especially weight and volume. Methods: This study was conducted on patients...

CASE REPORT A 57-year-old man presented with obstructive urinary symptoms for 6 months. Physical examination did not reveal any abnormality except for the slightly enlarged prostate. Prostate volume was estimated to be 55 mL, and serum level of prostate-specific antigen (PSA) was 5.4 ng/mL. Eight-quadrant transrectal biopsy revealed no malignancy. Transurethral prostate resection was done and p...