The purpose of the present work was to formulate and evaluate cationic poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) nanoparticles as novel non-viral gene delivery nano-device. Cationic PLA-PEG nanoparticles were prepared by nanoprecipitation method. The gene loaded nanoparticles were obtained by incubating the report gene pEGFP with cationic PLA-PEG nanoparticles. The physicochemical prope...

Cyclodextrin-conjugated poly(lactic acid)-b-poly(ethylene glycol) (β-CD-PLA-mPEG), a well-defined amphiphilic copolymer, was synthesized by controlled ring-open copolymerization and click coupling reaction, in order to obtain a biocompatible drug delivery system with controlled release profiles. The β-CD-PLA-mPEG copolymer could self-assemble in aqueous solution to form micelles with a mean par...

Nowadays, the use of biodegradable and bio-derived plastics such as poly(lactic acid) (PLA) cellulose in food packaging applications are replacing different more conventional oil-derived polymers that much expensive unsuitable for environment. However, their high transparency to ultraviolet (UV) radiation limits current commercialization. Therefore, this study focuses on deposition organic thin...

Abstract Chemical treatment can effectively reduce the surface roughness of fused deposition modeling (FDM) parts. An effort is made in this study to appraise finish poly lactic acid (PLA) parts by FDM with hot vapor smoothing treatment. The tests were designed as per Taguchi L16 orthogonal array based factorial design experimentation while varying process parameters such time, temperature and ...

Nanocomposites of poly(lactic acid) with sepiolite needles (5 wt.%) were evaluated in terms the mechanical and biofilm formation properties. The nanocomposite exhibited higher values Young�s modulus tensile strength at break compared to PLA, without detriment percent elongation break. These improvements related high aspect ratio nanoclay, polymer-clay interactions, degree dispersion. growth Pse...

Poly (lactic acid) (PLA) has a broad perspective for manufacturing green thermoplastic products by thermoforming its biodegradable properties. The mechanical behaviour of PLA been demonstrated strong dependence on temperature and strain rate at biaxial deformation. A nonlinear viscoelastic model the previous study was employed in process used food packaging. An optimisation approach developed a...

a-Tocopherol (a-TC) and a-TC/cyclodextrin (CD)–inclusion complex (IC) incorporated electrospun poly(lactic acid) (PLA) nanofibers (NF) were developed via electrospinning (PLA/a-TC–NF and PLA/a-TC/g-CD–IC–NF). The release of a-TC into 95% ethanol (fatty food simulant) was much greater from PLA/a-TC/g-CD–IC–NF than from PLA/a-TC–NF because of the solubility increase in a-TC; this was confirmed by...

Estimating the colloidal stability of polymeric nanoparticles (NPs) in biological environments is critical for designing optimal preparations and to clarify the fate of these devices after administration. To characterize and quantify the physical stability of nanodevices suitable for biomedical applications, spherical NPs composed of poly-lactic acid (PLA) and poly-methyl-methacrylate (PMMA), i...

The present study deals with the effects of alkaline and benzoyl chloride treatments sugar palm fibers (SPFs) on mechanical morphological properties SPF-reinforced poly(lactic acid) (PLA) composites. Seven different parameters SPFs were compared, which untreated, three solution concentrations 4%, 5%, 6% for treatment, 50 ml chloride-treated at soaking durations 10, 15, 20 min. Composites 30 wt....