Periodontal diseases are highly prevalent inflammatory diseases that lead to a destruction of tooth-supporting tissues, such as the periodontal ligament, alveolar bone and cementum, and ultimately result in tooth loss. Conventional treatment for periodontal diseases is the mechanical removal of the periodontal biofilm, which although effective in reducing inflammation in lesion sites, dose not ...

Background The present study aims to comparatively evaluate the isolation and quantification of stem cells derived from dental pulp and periodontal ligament of a permanent tooth and to assess their viability and proliferation on a platelet-rich fibrin (PRF) scaffold. Materials and Methods A total of 15 systemically healthy individuals between the age group of 15-25 years requiring third molar...

INTRODUCTION The purpose of this study was to quantify the effect of three different rotary root canal preparation systems on substance P and calcitonin gene-related peptide expression in healthy human periodontal ligament. METHODS Fifty periodontal ligament samples were obtained from healthy premolars in which extraction was indicated for orthodontic reasons. Before extraction, 40 of these p...

introduction: the purpose of this study was to evaluate external root surface temperature rise during post space preparation using la axxess bur, beefill pack system, and peeso reamer drill. materials & methods: the distal canals of forty-five extracted human permanent mandibular first molars were instrumented in crown-apical manner and obturated with lateral condensation technique. teeth were ...

Regeneration is defined as a reproduction or reconstruction of a lost or injured part in a way that both form and function of lost tissues are completely restored (Wikesjö and Selvig, 1999; Caton and Greenstein, 1993; Machtei, 1997; World Workshop in Periodontology, 1996). Regenerative periodontal therapy aims to predictably restore the tooth’s supporting apparatus which has been lost following...

Rat calvaria cells (RC cells) and monkey periodontal ligament fibroblasts (MPL cells) were cultured for 4-6 days with demineralized dentine, acid-washed glass particles or untreated glass particles to determine whether the presence of these particles can affect the orientation of the cells. Encapsulation of dentine particles began as early as the first day in culture and occasional cells were a...

The periodontal disease is a chronic, degenerative disease which is localised on the gingiva, periodontal ligament, cementum and alveolar bone. The main etiological factor is oral biofilm with microorganisms. The search for the pathogens of periodontal diseases has been underway for more than 100 years, and continues up today. The currently recognized key Gram negative periodontopathogens inclu...

The enamel matrix derivative Emdogain was recently approved for clinical use in a number of countries, including Canada. It has been shown to stimulate regeneration of periodontal ligament following periodontal surgery in adults. This paper reviews pertinent clinical and laboratory studies of Emdogain and describes the protocol and methods used for a longitudinal outcome study of replantation o...