BACKGROUND Gingival crevicular fluid (GCF) biomarkers associated with bone resorption may be useful to determine periodontal disease status and response to therapy. The pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen (ICTP), a bone-specific degradation product, and interleukin 1-beta (IL-1), a potent bone-resorptive cytokine, have both been associated with periodontal ...

context the aim of this review was to examine evidences for the association between smoking and periodontal disease, to discuss possible biological mechanisms whereby smoking may adversely affect the periodontium, and to consider the effect of smoking on periodontal treatment. evidence acquisition a web-based search in pubmed and google scholar was performed to identify publications regarding t...

background: rheumatoid arthritis (ra) is the most prevalent chronic infl ammatory disease of the joints. it is correlated with periodontal disease due to similar factors that exist in both diseases. the present study assessed the relationship of periodontal disease with ra and juvenile idiopathic arthritis (jia). materials and methods: in this case-control study, 30 ra and 30 jia patients along...

Periodontal disease is one of the most prevalent oral diseases. An association between this disease and pregnancy has been suggested, but available findings are controversial. We evaluated the expression levels of interleukins (IL-1β and IL-6), tumor necrosis factor-alpha (TNF-α), and inducible nitric oxide synthase (iNOS) in pregnant women with and without periodontal disease in comparison wit...

Numerous studies have demonstrated significant associations between periodontal disease and many other diseases in living populations, and some studies have shown that individuals with periodontal disease are at elevated risks of mortality. Recent analysis of a medieval skeletal sample from London has also shown that periodontal disease was associated with increased risks of mortality in the pa...

background : periodontal disease is a common oral disease, which oxidative stress plays an important role in its pathogenesis. the onset and progress of this disease is influenced by balance between oral biofilm and host response. regarding with the role of oxidative stress in the pathogenesis of periodontal disease and reduction of total antioxidant capacity in patients with periodontal diseas...

conclusions cigarette smoking increased some periodontal indexes including pcr and cal, and reduced bop (p < 0.05). results there was not a significant difference in the prevalence of isolated microorganisms between the smokers and nonsmokers. however, the cigarette smoking group had adverse effect on other periodontal indices including pcr, cal, and bop. the mean pcr and cal were significantly...

BACKGROUND The aim of this paper is to provide an overview of the burden of periodontal disease in adult populations worldwide, to emphasize the essential risk factors common to periodontal disease and chronic diseases, to outline important new strategies for effective prevention of periodontal disease, and to inform about the role of the World Health Organization (WHO) in developing a national...

OBJECTIVE The goal was to estimate whether maternal periodontal disease was predictive of preterm (less than 37 weeks) or very preterm (less than 32 weeks) births. METHODS A prospective study of obstetric outcomes, entitled Oral Conditions and Pregnancy (OCAP), was conducted with 1,020 pregnant women who received both an antepartum and postpartum periodontal examination. Predictive models wer...

Periodontal diseases are characterized by localized infections and inflammatory conditions that directly affect teeth supporting structures which are the major cause of tooth loss. Several studies have demonstrated the involvement of autoimmune responses in periodontal disease. Evidences of involvement of immunopathology have been reported in periodontal disease. Bacteria in the dental plaque i...