BACKGROUND The use of autogenous bone chips during guided bone regeneration procedures has remained the gold standard for bone grafting due to its excellent combination of osteoconduction, osteoinduction and osteogenesis. Recent protocols established by our group have characterized specific growth factors and cytokines released from autogenous bone that have the potential to be harvested and is...

various biological bone g rafts have been used for osteogenes i s , osteoconduction and even osteoinduction, but due to systemic influences and local factors, the outcome of successful incorporation of a bone graft has not been satisfactory. this study was therefore conducted on 15 clinically healthy adult dogs between 1 to 3 years of age weighing 20 to 30 kg to evaluate the effect of bone ceme...

A common procedure for donor allograft bone includes intraoperative sampling of the allograft for bacterial culture. The goal of this study was assess the clinical effectiveness of intra-operative cultures in identifying microorganisms in donor bone allografts. Retrospective data were collected from 205 patients (230 allografts) to assess the clinical effectiveness of intra-operative cultures i...

Introduction: Bone impaction grafting (BIG) is a surgical technique for the restoration of bone stock loss in revision total hip arthroplasty (rTHA) by impaction of allograft bone particles (BoP) into the bony defect. BoP are considered to be the gold standard, although many alternative materials have been developed, most of them being ceramic based. Important properties of these synthetic mate...

The development of implantology requires enough bone support, sufficient bone architecture. The use of autograft remains the gold standard; however the surgeons use cortical bone coming from mandibular part or craniofacial site, involving severe anaesthetic bone loss. The strategy of bone substitutes in place of autograft can be an efficient method. Several patients having a sinus lift augmenta...

INTRODUCTION: Osteoporotic fracture is one of the commonest geriatric orthopaedic problems. The deterioration in microarchitecture and decrease in bone mineral density (BMD) in osteoporotic bone reduce its “holding power” to implants. Subsequently, osteoporotic fractures are difficult to be fixed and remain major challenge to surgeons (1). Intensive in vivo studies are necessary for testing the...

Introduction The ideal bone substitute is a material that can be completely replaced by newly formed bone. Hydroxyapatite has been widely used as a bone substitute because of its excellent biocompatibility and osteoconductive ability. The clinical application of hydroxyapatite may be limited, because it does not seem to be resorbed appreciably. In order to improve these disadvantages, we have s...

Various materials are used in modern dental and maxillofacial surgery for bone tissue substitution and reconstruction. All osteoplastic materials can be divided into four groups by origin: autogenic, allogenic, xenogenic and synthetic. Synthetic resorbable materials were intended as an inexpensive substitute for natural bone. Synthetic graft materials include various types of ceramics: tricalci...

Objective. This work evaluated sciatic nerve regeneration after cryotherapy. Study design. Rats underwent surgical access of the sciatic nerve and subsequent cryotherapy, crush lesion or no manipulation. Walking-track, electroneuromyographic and histomorphometric analyses were performed at 15, 30 and 70 postoperative days. Results. At 15 days, the crush and cryotherapy groups showed significant...