Submit Manuscript | http://medcraveonline.com leading to a decrease in the working capacity and quality of life of a woman. By definition, cystitis is an infectious-inflammatory process in the wall of the bladder, mainly in the mucous membrane [1]. This disease is very common: the incidence rate among women 20-40 years is 25-35%. About 30% of women throughout their lives at least once fall ill ...

Interstitial cystitis (IC) is a chronic bladder inflammatory disease of unknown etiology that is often regarded as a neurogenic cystitis. IC is associated with urothelial lesions, voiding dysfunction, and pain in the pelvic/perineal area, and diet can exacerbate IC symptoms. In this study, we used a murine neurogenic cystitis model to investigate the development of pelvic pain behavior. Neuroge...

The aim of this study was to demonstrate and assess C-reactive protein (CRP) changes in dogs with induced bacterial cystitis with or without antibiotics. We also evaluated availability of CRP levels to serve as an indicator for monitoring or diagnosing bacterial cystitis. Serial CRP concentrations in dogs with induced bacterial cystitis were higher than those of controls (p < 0.001). CRP concen...

Introduction: Cystitis has high incidence in female population. Inflammation is responsible of irritative symptoms; it is supposed the existence of an arterial obstructive disease connected with bladder ischaemia. Direct bacterial damage and/or inflammation are responsible of the activation of ROS (radicals of oxygen) and consequent cell damage. NF-kB protein is protagonist in ROS synthesis. Hi...

OBJECTIVE To investigate the efficacy of hydrogen-rich water for the treatment of patients with interstitial cystitis/painful bladder syndrome (IC/PBS). METHODS We conducted a prospective, randomized, double-blind, placebo-controlled clinical trial of hydrogen-rich water in patients with IC/PBS. Inclusion criteria were stable symptoms of IC/PBS for ≥ 12 weeks after bladder hydrodistension, In...