Our capacity to model human disease through genetic manipulation has made the mouse (Mus musculus) one of the most important entities in biomedicine. Transgenic and targeted genetic mouse models of neurodegenerative disease are typically engineered on a mixed background of inbred mouse lines, i.e., 129/Sv and C57BL/6. These inbred strains display significant neuroanatomical differences. The cer...

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Herbal medicine (HM) is a fruitful source of chemical substances that has contributed greatly to the pharmaceutical industry and novel therapeutics. Natural products derived from HM continue be rich lead compounds because their high structural diversity potent bioactivities. However, despite success active ingredients in drug discovery, compatibility issues make huge challenging for extended ti...

Multi-omics data is frequently measured to enrich the comprehension of biological mechanisms underlying certain phenotypes. However, due complex relations and high dimension multi-omics data, it difficult associate omics features traits interest. For example, clinically valuable breast cancer subtypes are well-defined at molecular level, but poorly classified using gene expression data. Here, w...

The term “Omics” broadly refers to a set of genomics technologies that are utilized in cellular and molecular biology investigate (DNA, RNA), protein epigenetics signatures. Omics study both host pathogens, across many disciplines such as immunology, oncology cell biology. With the high-throughput development new bioinformatics tools, these approaches have significantly contributed our understa...