The present study was conducted to evaluate the hepatoprotective effects of an aqueous leaf extract of Coccinia grandis on carbon tetrachloride (CCl4) induced liver damage in albino rats. Wistar albino rats weighing around 180-200g were used. Toxicity was induced by using 30% CCl4 suspended in olive oil (1.0 ml/kg body wt intraperitoneal) after every 72 hrs for 3doses. The aqueous leaf extract ...

Medicinal plants are an important source of substances which are claimed to induce anti-inflammatory and antioxidant effects. The leaves of the olive tree (Oleaeur opaea) have been used for medicinal purposes since ancient times and research has suggested that olive leaf extracts have antimicrobial and antimutagenic properties. In this study, Olive leaf aqueous extracts were screened for their ...

A novel approach for the authentication of olive oil samples representing different quality grades has been developed. A new type of ion source, direct analysis in real time (DART), coupled to a high-resolution time-of-flight mass spectrometer (TOFMS) was employed for the comprehensive profiling of triacylglycerols (TAGs) and/or polar compounds extracted with a methanol-water mixture. The main ...

There is increasing evidence that menopause due to oxidative imbalance will lead to metabolic disorders (1). Menopause also increases food intake and body weight gain and is associated with abnormalities in lipid metabolism (2). More recent experimental studies confirm that ovariectomy cause oxidative stress and cell damage in animals (1,3,4). Steroid hormones, particularly estrogen, are natura...

We investigated the inhibitory effect of Cyclocarya paliurus (Batal.) Iljinskaja (C. paliurus) extract on postprandial hyperlipemia in mice. A single oral administration of C. paliurus extract (250 mg/kg) suppressed an increase in plasma triacylgycerol (TG) levels when fed with 5 ml/kg of lard and olive oil. The inhibition rates were 28.6% and 24.1%, respectively, but free fatty acid (FFA) leve...

The protective effect of olive mill pomace (OMP) loaded ethylcellulose microparticles as an alternative to synthetic antioxidants against the oxidation oils was assessed. OMP extract obtained by optimized two-step solid-liquid extraction; encapsulation performed double emulsion solvent evaporation technique considering a theoretical loading content in phenolic compounds 5% (w/w). changes peroxi...

Hydroxytyrosol (HT) is one of the most powerful natural antioxidants, mainly contained in olive oil and its by-products. Here, a procedure for preparation an HT-enriched sample described. An acidic aqueous extract (pH 1.25) from Olive Oil Dregs (OOD), by-product mills, was prepared by incubation at 37 °C 1 h. The total phenolic content HT amount were 6.24 ± 0.10 mg gallic acid equivalent/g OOD ...

BACKGROUND Liver diseases are major global health problems. Ginseng extract has antioxidant, immune-modulatory and anti-inflammatory activities. This study investigated the effect of ginseng extract on carbon tetrachloride (CCl4)-induced liver fibrosis in rats. METHODS Male Wistar rats were divided into four groups: control group, ginseng group, CCl4 group and CCl4 + ginseng group. Liver inju...

The atherosclerotic effect of Methanolic extract of Cleome viscosa was studied in Streptozotocin induced Diabetic Rats fed with Atherogenic Diet [1.5 ml olive oil containing 8 mg of vitamin D-2 and 40 mg cholesterol] for 5 consecutive days. Oral administration of extract to diabetic rats [250 mg/kg and 500 mg/kg for 30 days] produced significant (p<0.01) fall in fasting blood glucose levels in ...