Alzheimer’s disease is the most frequent type of life threatening dementia which is characterized by oxidative stress and inflammation induced neuronal loss, impaired energy metabolism, and cholinergic deficits leading to severe cognitive impairments and other abnormal neuropsychiatric changes. Cure of cognitive disorders such as amnesia, attention deficit and Alzheimer’s disease is still a nig...

This study aimed to investigate the beneficial effects of tocotrienols (T3) supplementation on one’s attention and memory. Eleven healthy subjects were enrolled receive placebo followed by T3 in 6 weeks. Psychomotor Vigilance Task (PVT) Digit Span Test (DST) used access subjects’ sustained working Electroencephalogram (EEG) was examine brainwave activity. significantly improved memory relative ...

The review presents the results of studies on pharmacokinetics, metabolism, and bioavailability new neurotropic dipeptide cyclo-Lprolilglycine (CPG) their pharmacological activity. It was shown that pharmacologically active metabolite nootropic drug noopept is an endogenous dipeptide, it a fragment terminal Tripeptide insulin-like nerve growth factor IGF-1. Much attention paid both in Russia ab...

This study investigated the effects of nicotine on memory and learning in adolescent and adult male Fischer-344 rats. Rats were given 0.2 mg/kg/day of either nicotine or saline chronically for 2 weeks and were tested in the Morris water maze as adolescents (Phase 1) and then again 4 months later as adults (Phase 2). There were 4 main groups: nicotine/nicotine, nicotine/saline, saline/nicotine, ...