Both polycystic liver disease (PLD) and sarcoidosis can involve liver. Most of the time, liver disease in both conditions is asymptomatic, but they can rarely cause portal hypertension. Our aim is to report a case of a 51-year-old female with a history of adult dominant polycystic kidney disease (ADPKD) and sarcoidosis who presented with multiple episodes of hematemesis. An endoscopy showed gra...

introduction and aims: impact of treatment on progression of fibrosis in autoimmune hepatitis (aih) is unknown. we assessed the changes in liver fibrosis before and after treatment among these patients. materials and methods: nineteen aih patients who had paired liver biopsies were studied. of these, seven had been treated with 6 months of cyclosporine-a and the rest with 6 months of prednisolo...

It is now known that the liver is often damaged in fibrocystic disease of the pancreas. Bodian (1952) found patchy portal fibrosis and an increase in bileduct structures, which he termed focal biliary fibrosis, in half of the 50 cases in his series in which histological sections of liver were available. This lesion is found most often and most severely in older children, but Claireaux (1956) ha...

Introduction: Nodular fasciitis is described as a benign reactive proliferation of myofibroblasts. Due to its rapid-growing nature, a precise clinical diagnosis is difficult and the condition is frequently misdiagnosed as malignant lesions.   Case Report: In this study, we present the case of a young woman with an auricular nodular fasciitis as an example of one of the rarest sites of this tumo...

BACKGROUND Coal workers' pneumoconiosis (CWP), resulting from the inhalation of silica-containing coal mine dust, is characterized by fibrosing nodular lesions that eventually develop into progressive pulmonary fibrosis. Recently, it has been hypothesized that inflammasomes could have a crucial role in the host response to silica and recent studies show that the inflammasome contributes to infl...

We investigated the effects of a high-cholesterol (HC) diet administered long term (25 or 55 weeks) on metabolic disorders including hepatic damage in mice. The mice were fed the HC diet (15 % milk fat, 1.5 % cholesterol and 0.1 % cholic acid, w/w) for 25 or 55 weeks. Body and adipose tissue weights were similar to those of mice fed a control diet. Consumption of the HC diet long term resulted ...

Sarcoidosis is a multisystemic disorder that is characterized by the formation of noncaseating granulomas. Although sarcoidosis can affect any organ, gastrointestinal tract involvement in sarcoidosis is very rare, and gastric cancer associated with gastric sarcoidosis has hardly been reported. A 64-year-old female with a 10-year history of the medical treatment of gastric sarcoidosis received a...

Objective To describe the various mechanisms of liver disease in patients with HIV infection, and to link these mechanisms to disease states which may utilise them. Background Non-AIDS causes of morbidity and mortality are becoming increasingly common in patients chronically infected with HIV. In particular, liver-related diseases have risen to become one of the leading causes of non-AIDS-rel...

In 1953 a new syndrome was described in which the association of rheumatoid arthritis with nodular fibrosis of the lung parenchyma was noted (Caplan, 1953). Though this condition resembles progressive massive fibrosis in some ways, there are certain distinctive features. The opacities that are found in Caplan's syndrome are usually more peripherally situated, tend to be multiple, and more commo...