Background Nucleus basalis of Meynert (NbM) is the main source cholinergic projection to cerebral cortex, including entorhinal cortex (EC). Both cells NbM and their receptive targets in EC show degeneration during early stages Alzheimer’s disease (AD). While precise delineation region on T1w scans difficult due limited spatial resolution contrast, we sought quantify along trajectory confirm rec...

The basal forebrain (BF) is poised to play an important neuromodulatory role in brain regions important to cognition due to its broad projections and complex neurochemistry. While significant in vivo work has been done to elaborate BF function in nonhuman rodents and primates, comparatively limited work has examined the in vivo function of the human BF. In the current study we used multi-echo r...

The expression of HLA-DR antigens by normal myeloid progenitor cells (CFU-GM) has been linked to inhibition of colony growth by prostaglandin E (PGE), while resistance to the inhibitory effects of PGE in chronic myeloid leukemia (CML) has been attributed to a lower fraction of HLA-DR+ CFU-GM in this disease. However, we have previously shown that virtually all CFU-GM in normal bone marrow (NBM)...

BACKGROUND Soluble oligomeric (misfolded) species of amyloid-β (Aβ) are the main mediators of toxicity in Alzheimer's disease (AD). These oligomers subsequently form aggregates of insoluble fibrils that precipitate as extracellular and perivascular plaques in the brain. Active immunization against Aβ is a promising disease modifying strategy. However, eliciting an immune response against Aβ in ...

Objectives- To assess the ectopic bone formation in canine masseter muscle following the implantation of the natural bovine bone minerals (NBM) loaded with canine mesenchymal stem cells (MSCs).Design- Experimental study.Animals- four mongrel dogs.Procedures- Tripotent MSCs isolated from the canine bone marrow were loaded onto the NBM sponges and allowed to adhere. The cell-loaded scaffolds were...

Wind turbine gearbox condition monitoring (C&M) is a key technology to promote wind farm maintenance cost reduction and power generation improvement. Existing C&M methods usually adopt the component-by-component modelling approach. Firstly, this approach inefficient in modelling; secondly, due thermal conduction effect, abnormalities one component affect other components, making it difficult id...

Pendahuluan: Perkembangan teknologi industri kian hari berkembang. Digitalisasi yang terjadi pada sektor perkantoran dapat dilihat dari cepatnya penyebaran dan penerimaan informasi. Kemudahan digitalisasi kebutuhan semakin kompleks tentunya juga berpengaruh peningkatan interaksi manusia-mesin di dalamnya. Tujuan penelitian ini adalah untuk mengetahui Prevalensi Resiko Ergonomi Pada Kejadian Mus...

The cover image is based on the Research Article A strategy to prevent a temperature-induced MRI artifact in warm liquid phantoms due convection currents by Ryan T. Oglesby, Wilfred W. Lam, and Greg J. Stanisz., https://doi.org/10.1002/nbm.4494.

ADAS-cog 1⁄4 Alzheimer’s disease Assessment Scale, MMSE 1⁄4Mini Mental Status Examination, RWT 1⁄4 Regensburger Wortschatz Test, WAIS 1⁄4 Wechsler Adult Intelligence Scale, WMS 1⁄4 Wechsler Memory Scale, BDI II 1⁄4 Beck’s Depression Inventory (2nd edition), HAMD 1⁄4 Hamilton Depression Rating Scale, FAST 1⁄4 Florida Apraxia Screening Test. a A lower value represents a better outcome. b A higher...

Small Medium Enterprise (SMEs) hold a strategic role in economic activities. Since SMEs contribute enlivening businesses, it is important to assess the SMEs’ performances. One of most vital aspects running workers’ productivity which very risky declining performance. This study will Musculoskeletal Disorder (MSD), one problems. By applying Nordic Body Map (NBM) and Rapid Upper Limb Assessment (...