INTRODUCTION Alzheimer's disease (AD) is characterized by progression of memory problems to a slow global decline of cognitive function. Inflammation when left unregulated becomes a major cofactor in the pathogenesis of AD. PTGS2 is of crucial relevance in the inflammatory response, and it has been shown to play a considerable role in AD pathogenesis. MATERIAL AND METHODS To assess the possib...

Author details Maxillofacial Surgery Department, Sant’Andrea Hospital, “Sapienza” University of Rome, Rome, Italy. Maxillofacial Surgery Department, Azienda Ospedaliera Universitaria Pisana of Pisa, Pisa, Italy. Maxillofacial Surgery Department, University of study of Messina, Messina, Italy. Maxillofacial Surgery Department, Federico II University of Naples, Naples, Italy. Maxillofacial Surger...

1Department of Clinical and Experimental Medicine, University of Messina, Viale Gazzi, 98123 Messina, Italy 2Institute of Molecular BioMedicine, Medical Faculty, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia 3Department of Internal Medicine, Service of Nephrology, University Hospital (CHUV), Avenue du Bugnon 17, 1011 Lausanne, Switzerland 4Nephrology, Med School, Second Universi...

1Department of Experimental Medicine, Division of Pharmacology, Second University of Naples, 80138 Naples, Italy 2Wolfson Centre for Age Related Diseases, King’s College London, Guy’s Campus, London SE1 1UL, UK 3Saint Louis University School of Medicine, Saint Louis, MO 63104, USA 4Laboratory of Pain Pathophysiology, Department of Pain Pharmacology, Institute of Pharmacology, Polish Academy of ...

Background: Overweight and obesity represents a complex interaction of genetics, diet, metabolism, and physical activity. Abnormal or excessive body fat accumulation increases the risk of pathologies, such as heart disease, diabetes, and high blood pressure. Methods and results: In a previous paper, we investigated the influence of overweight individuals’ sera on in vitro biology of mesenchymal...