نتایج جستجو برای: myelodysplastic syndromes
تعداد نتایج: 86513 فیلتر نتایج به سال:
We performed a phase I/Il study of the administration of recombinant human granulocyte-macrophage colonystimulating factor (GM-CSF) to patients with aplastic anemia or myelodysplastic syndrome. Doses ranging from 15 to 480 .tg/m2 were administered as a one-hour or fourhour intravenous infusion daily for 7 days or as a 1 2-hour infusion for 1 4 days. Temporary improvements were seen in granulocy...
BACKGROUND AND OBJECTIVES Clonal hematopoiesis is the hallmark of myelodysplastic syndromes, but the role played by pluripotent stem cells and progenitor cells in these disorders remains unclear. DESIGN AND METHODS Eight female patients with myelodysplastic syndrome were studied. X-chromosome inactivation patterns were analyzed in peripheral blood granulocytes, T-lymphocytes, single colonies ...
BACKGROUND An alternative reduced-toxicity conditioning regimen for allogeneic transplantation, based on treosulfan and fludarabine, has recently been identified. The rationale for this study was to investigate the efficacy and safety of this regimen prospectively in patients with a primary myelodysplastic syndrome. DESIGN AND METHODS A total of 45 patients with primary myelodysplastic syndro...
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