The neuronal physiological correlates of clinical heterogeneity in human essential tremor are unknown. We now test the hypothesis that thalamic neuronal and EMG activities during intention essential tremor are similar to those of the intention tremor which is characteristic of cerebellar lesions. Thalamic neuronal firing was studied in a cerebellar relay nucleus (ventral intermediate, Vim) and ...

INTRODUCTION Re-emergent tremor (RET) is a postural tremor that appears after a variable delay in patients with Parkinson's disease (PD). The aim of the present study was to evaluate the occurrence and the clinical characteristics of RET in a population of patients with PD. METHODS We consecutively assessed 210 patients with PD. We collected the patients' demographic and clinical data. RET wa...

BACKGROUND AND PURPOSE Action tremor may occur in patients with Parkinson's disease and cause misdiagnosis with other movement disorders such as essential tremor and dystonia. Data on the frequency of action tremor in Parkinson's disease and on the relationships with other motor and non-motor signs are limited. METHODS A cross-sectional study of 237 patients with Parkinson's disease staging 1...

This work quantifies and analyzes tremor using Ultra Wide Band (UWB) radio technology. The UWB technology provides a new technology for non contact tremor assessment with extremely low radiation and penetration through walls. Tremor is the target symptom in the treatment of many neurological disorders such as Parkinson’s disease (PD), midbrain tremor, essential tremor (ET) and epilepsy. The com...

The hallmark feature of essential tremor (ET) is action tremor of the arms. Leg tremor may also occur yet it has not been the central focus of previous studies. Its prevalence has only rarely been reported, its clinical correlates have yet to be explored. Our aims were to report the prevalence and analyze the clinical correlates of leg action tremor in patients with ET and, given the propensity...

Background Head tremor may be observed in the presence of cervical dystonia and sometimes coexists with headache. We wished to investigate the presence of headache in dystonic head tremor. Methods We studied the files of 19 patients from our outpatient clinic (1997-2017) with dystonic head tremor and assessed the co-occurrence of headache. We also performed a literature search of the topic. ...

Tremor is the root cause for human imprecision during microsurgery. Accurate filtering of physiological tremor is extremely important for compensation in robotics assisted microsurgical instruments/ procedures. A study on several surgeons tremor is conducted and the characteristics of the tremor are analyzed. A double adaptive bandlimited multiple Fourier linear combiner is designed to estimate...

This paper reports the study and results of modeling and online compensating of movement disorder stemming from multiple sclerosis (MS) via artificial neural networks. We trained and tested a cascade-correlation neural network with Kalman filtering on data collected from 11 subjects with MS. The test subjects use headcontrolled mouse emulators to move a cursor to a series of random targets on s...

After the introduction of levodopa drugs in the late 1960s, the number of thalamotomies fell dramatically world wide. However, as the Parkinsonian tremor proved rather resistant to levodopa treatment, the interest in this operation has been reviewed. During 1978-86, 51 stereotaxic thalamotomies were performed in 48 patient in our department. Thirty three of these patients had Parkinsonism, nine...

In the clinic, tremor is diagnosed during a time-limited process in which patients are observed and the characteristics of tremor are visually assessed. For some tremor disorders, a more detailed analysis of these characteristics is needed. Accelerometry and electromyography can be used to obtain a better insight into tremor. Typically, routine clinical assessment of accelerometry and electromy...