We assessed whether fetal growth restriction without pregnancy-induced hypertension (PIH) is associated with the different clinical subgroups of PIH in the subsequent pregnancy. We also assessed the maternal and paternal contributions to this effect. Pairs of first and second, second and third, third and fourth, and fourth and fifth births were identified among all of the births in Norway: 137 ...

Objectives: To study the role of β – hCG in pathogenesis of preeclampsia and its association with severity of preeclampsia. Materials and Methods: The prospective randomized study was conducted on 500 pregnant women of gestational pregnancy between 12 24 weeks with singleton pregnancy. According to American college of obstetrics and gynecology [ACOG, 2013], patients were classified into three g...

Hypertensive disorders of pregnancy, including pre-existing and gestational hypertension, preeclampsia eclampsia, complicate up to 10% pregnancies represent a significant cause maternal perinatal morbidity mortality. Despite some differences in guidelines, there is consensus that severe hypertension mild with organ dysfunction should be managed. However, achieving target values below 160/110 mm...

Background: Preeclampsia and eclampsia have been recognized as clinical entities since the times of Hippocrates. Pregnancy induced hypertension (PIH) is one of the commonest disorders associated with the increased risk of maternal and fetal complications. It is reported in the world literature that the incidence of eclampsia is on the decline, but still a menace in developing countries. Objecti...

background: preeclampsia is a serious complication of pregnancy, and it is vital to diagnosis the condition as early as possible. proteinuria is an important symptom of preeclampsia, and repeated urine analysis to screen for the condition is part of the standard antenatal care. the purpose of this study was to determine the correlation between 4- and 24-hour urine total protein values to examin...

Preeclampsia is a major cause of maternal and perinatal mortality and morbidities worldwide, and its etiology remains unknown. The reported incidence of preeclampsia in healthy nulliparous women is approximately 6%, with 93% of cases developing at 34 weeks gestation.1 Knowledge about the pathogenesis of preeclampsia has changed significantly over the past decade by virtue of increased recogniti...

Hypertensive disorders of pregnancy (HDP) are a group of medical complications in pregnancy and also a risk factor for severe pregnancy outcomes, but it lacks a large-scale epidemiological investigation in recent years. This survey represents a multicenter cross-sectional retrospective study to estimate the prevalence and analyze the risk factors for HDP among the pregnant women who had referre...

• Describe the pathophysiology of preeclampsia and eclampsia. • Differentiate the management of the woman with mild preeclampsia from that of the woman with severe preeclampsia. • Identify the priorities for management of eclamptic seizures. • Describe HELLP syndrome, including appropriate nursing actions. • Explain the effects of hyperemesis gravidarum on maternal and fetal well-being. • Discu...

Variations in genes involved in DNA repair systems have been proposed as risk factors for the development of preeclampsia (PE). We conducted a case-control study to investigate the association of Human apurinic/apyrimidinic (AP) endonuclease (APEX1) Asp148Glu (rs1130409), Xeroderma Pigmentosum group D (XPD) Lys751Gln (rs13181), X-ray repair cross-complementing group 1 (XRCC) Arg399Gln (rs25487)...

OBJECTIVE We investigated the influence of acute hypoxia on the placental vascular endothelial growth factor system in vitro and in vivo in acute birth asphyxia compared with pregnancies that were complicated by preeclampsia and with healthy control subjects. STUDY DESIGN Messenger RNA levels for vascular endothelial growth factor, flt-1, and KDR were measured by TaqMan real-time polymerase c...