For a better understanding of the dynamics of exotic nuclei it is of crucial importance to develop a practical microscopic theory easy to be applied to a wide range of masses. Theoretically the basic task consists in formulating an easy solvable theory able to reproduce structures and transitions of known nuclei which should be then used to calculate the sparely known properties of protonor neu...

Companion diagnostics are integral to the application and success of personalized medicine. In oncology, many companion diagnostics are molecular-based, including a number of fluorescence in situ hybridization (FISH) based companion diagnostics. Here, we review the currently approved FISH based companion diagnostics and evaluate several new FISH assays as potential companion diagnostics.

We analyzed Medical Subject Headings (MeSH) from 21.6 million research articles indexed by PubMed to map this vast space of entities and their relations, providing insights into the origins future biomedical convergence. Detailed analysis MeSH co-occurrence networks identifies three robust knowledge clusters: universe microscopic biological structures; systems, disease diagnostics; emergent soc...

A new hepatitis C virus (HCV) core antigen (HCV Ag) assay was thought to have a good correlation with HCV RNA. The aim was to elucidate the usefulness of this HCV Ag assay in community screening. In a township where HCV is endemic, 405 residents aged 58 years or older responded to a follow-up community screening. All subjects were tested for anti-HCV (AxSYM, version 3.0; Abbott Diagnostics) and...

The concept of integrated data analysis in nuclear fusion requires the linkage of data and physical information. Summarizing the key steps for the analysis of transport in the core plasma, benefits of probabilistic modelling of single diagnostics are discussed. Concepts for full diagnostics models consisting of several diagnostics modules and linkage through mapping procedures are given in figu...