Protein isoaspartyl methyltransferase is implicated in the repair of age-damaged proteins containing atypical, isoaspartyl linkages. To test the prediction that isoaspartyl proteins would accumulate during methyltransferase inhibition, rat PC12 cells were treated with the indirect methylation inhibitor, adenosine dialdehyde. We observed a marked, dose- and time-dependent, reversible accumulatio...

The template-directed construction of crown-ether-like macrocycles around secondary dialkylammonium ions (R2NH2+) has been utilized for the expedient (one-pot) and high-yielding synthesis of a diverse range of mechanically interlocked molecules. The clipping together of appropriately designed dialdehyde and diamine compounds around R2NH2+-containing dumbbell-shaped components proceeds through t...

Bacterial cellulose (BC) is an alternative nanostructured biomaterial to be utilized for a wide range of biomedical applications. Because of its low bioactivity, which restricted its practical application, collagen and collagen hydrolysate were usually composited into BC. It is necessary to develop a new method to generate covalent bonds between collagen and cellulose to improve the immobilizat...

The work studied weight losses of harvested strawberries provided with protective edible coating. Coatings were produced by dipping strawberries in 50 % (w/w) starch-protein hydrolysate of Amaranth flour. Tests investigated influence of added glycerol (10 or 30 %) and dialdehyde starch (1 or 4 %) on barrier properties. A protective film was produced on the strawberries after drying 5 min. at 23...

We report on multicomponent self-sorting to form open circular helicates of different sizes from a primary monoamine, Fe(II) ions, and dialdehyde ligand strands that differ in length and structure by only two oxygen atoms. The corresponding closed circular helicates that are formed from a diamine--a molecular Solomon link and a pentafoil knot--also self-sort, but up to two of the Solomon-link-f...

Chemical modification of naturally occurring polysaccharide, guaran has been made by incorporating 5aminosalicylic hydroxamate moiety to improve its selectivity and capacity for heavy metal ions. 5Amino salicylic acid hydroxamate derivative of guaran (ASAH-G) was synthesized, characterized and its adsorption behavior with Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), U(VI), W(VI), Cr(VI) and ...

Abstract. Reactions in aqueous solutions containing dicarbonyls (especially the α-dicarbonyls methylglyoxal, glyoxal, and biacetyl) reduced nitrogen (NHx) have been studied extensively. It has proposed that accretion reactions from NHx could be a source of particulate matter brown carbon atmosphere therefore direct implications for human health climate. Other dicarbonyls, such as 1,4-unsaturate...