Background: Among the non-surgical methods of preventing conception, taking oral contraceptive pills is the most common way. Some of the studies have shown that contraceptive pills due to containing estrogen and progesterone cause lipid peroxidation and as a consequence increase the level of oxidative stress. Aim: To compare the level of plasma Malone dialdehide in LD contraceptive pill and con...

background & aim:  ulcer index is one of the most common diseases among people. current therapies include acid secretion inhibitors which have various side effects. herbal medicines are considered as adjuvant therapy for this disease. hydroalcoholic extract of thymus daenensis has various components such as flavonoids which contribute to gastroprotection. experimental: 35 sprague dawley rat...

Prohibitin is an evolutionary conserved and pleiotropic protein that has been implicated in various cellular functions, including proliferation, tumour suppression, apoptosis, transcription, and mitochondrial protein folding. We recently demonstrated that prohibitin downregulation results in increased renal interstitial fibrosis. Here we investigated the role of oxidative stress and prohibitin ...

The antioxidant activities of the crude hydro-alcoholic extract (CE) and its four fractions viz. methanol (MF), ethyl acetate (EF), n-Butanol (BF), and precipitated aqueous (PAF) of A.racemosus roots tested decreased in the order of EF > MF > CE > BF > PAF when investigated by DPPH free radical scavenging assay. Under iron induced lipid peroxidation almost similar results were observed except t...

Reactive oxygen species (ROS) have been implemented in the etiology of pulmonary fibrosis (PF) in systemic sclerosis. In the bleomycin model, we evaluated the role of acquired mutations in mitochondrial DNA (mtDNA) and respiratory chain defects as a trigger of ROS formation and fibrogenesis. Adult male Wistar rats received a single intratracheal instillation of bleomycin and their lungs were ex...

Prohibitin is an evolutionary conserved and pleiotropic protein that has been implicated in various cellular functions, including proliferation, tumour suppression, apoptosis, transcription, and mitochondrial protein folding. Both prohibitin over- and under-expression have been implicated in various diseases and cell types. We recently demonstrated that prohibitin down-regulation results in inc...

This study evaluates the effects of polyphenolic extract Cistus incanus, lycopene dye from tomatoes, and betanin red beet on selected parameters model meat products with reduced nitrate contents. The composition activity C. incanus was analyzed, revealing presence elagotannins, flavanols, glycosylated flavanols. We studied dyes as well mixtures growth bacteria characteristic environment: E. col...

Background Any factor like diabetes that changes the oxidant/antioxidant balance in favor of oxidants could possibly disrupt the physiologic function of ovaries. So, we have investigated the effect of vitamin E and Se supplements on antioxidant defense in ovaries of diabetic rats with focus on Xanthine dehydrogenase/oxidase (XDH/XO) and Aldehyde oxidase (AO) activities. MaterialsAndMethods This...