Diffuse large B cell lymphoma (DLBCL) is a frequent aggressive subtype of non-Hodgkin lymphoma, representing nearly 30-40% all cases. The skin may be affected by the disease either primarily or secondarily. Herein we report clinical and dermoscopic case metastasis DLBCL in patient with Klinefelter Syndrome.

  Background and Objectives: Epstein Barr Virus (EBV) is one of the members of herpesviridae family and a sub-category of Gamma herpes virinae. EBV, which normally has CR2 or CD21 receptors on B-lymphocytes, has mutagenic features for them. The virus plays an important role in causing some malignant cancers. About 30% of the cases with non-Hodgkin’s lymphoma are diffuse large B-cell l...

Non-Hodgkin lymphoma (NHL) comprises of heterogeneous group lymphoid malignancies originating from lympho-reticular tissues and is quite uncommon in pregnancy (0.8 cases per 1,00,000 women). Anaplastic large cell (ALCL) a large-cell neoplasm with anaplastic morphology classified under NHL. Here, 31 year old primigravida diagnosed NHL ALCL subtype third trimester, started on chemotherapy which r...

Cutaneous round cell tumors have been classified as mast cell tumor (MCT), histiocytoma (HCT), lymphosarcoma, undif-ferentiated round cell tumors and occasionally rhabdomyosarcoma in veterinary medicine. An adult cock (Gallus domesticus) showing a large solitary integument mass raised on dorso bilateral of cervical part, extending to intercapsular and cranial mid part of the back was referred t...

Primary mediastinal large B-cell lymphoma is a subtype of diffuse large B-cell lymphoma, arising in the mediastinum from putative thymic B-cell origin with distinctive clinical and genetic features. Generally, primary mediastinal large B-cell lymphoma is believed as only deriving in the mediastinum. The current study presents a rare case of primary mediastinal large B-cell lymphoma which arisin...

peripheral t-cell lymphomas are a group of heterogeneous disorders and according to who classification, are categorized into nodal and extranodal forms. nk/t-cell lymphoma, nasal type, is a subtype of extranodal peripheral t-cell lymphoma and commonly presents as a midfacial destructive lesion. this disorder is more prevalent in asia and south america and has a strong association with epstein b...

The overlapping features of malignant lymphomas create a diagnostic "grey zone" , and lead to the invention of "grey zone lymphomas". There are several major grey zone lymphomas: 1) Lymphomas with overlapping features of Hodgkin lymphoma and large B-cell lymphoma; 2) Lymphomas with overlapping features of Burkitt lymphoma and diffuse large B-cell lymphoma; 3) Lymphomas with overlapping features...

Anaplastic large-cell lymphoma (ALCL) is a CD30-positive T-cell/null-cell lymphoma that is clinically classified into either primary cutaneous ALCL or systemic ALCL (S-ALCL) sub-types. Because 90% of childhood S-ALCL cases are anaplastic lymphoma kinase (ALK)-positive, there is a lack of data on ALK-negative S-ALCL cases among pediatric patients. Herein, we report a rare case of ALK-negative S-...