Undernourishment in HIV infected individuals exacerbates immunosuppression, acceleration of HIV replication and CD4 + T cell depletion. The production of human milk (lactogenesis) is dependent on factors in the blood therefore deranged blood parameters in HIV patients are expected to reflect in the components of breast milk. Study on effects of HIV infection on nutritional components of breast ...

Prolactin (PRL) is an anterior pituitary hormone with a broad range of functions. Its ability to stimulate lactogenesis, maternal behavior, growth and development, osmoregulation, and epithelial ion transport has been reported in many vertebrates. In our present study, we have targeted the zebrafish prl locus via transcription activator-like effector nucleases (TALENs). Two independent targeted...

BACKGROUND Preeclampsia is a multi-system, hypertensive disorder of pregnancy that increases a woman's risk of later-life cardiovascular disease. Breastfeeding may counteract the negative cardiovascular sequela associated with preeclampsia; however, women who develop preeclampsia may be at-risk for suboptimal breastfeeding rates. In this case series, we present three cases of late-onset preecla...

During lactation, branched-chain aminotransferase (BCAT) gene expression increases in the mammary gland. To determine the cell type and whether this induction is present only during lactation, female rats were randomly assigned to one of three experimental groups: pregnancy, lactation, or postweaning. Mammary gland BCAT activity during the first days of pregnancy was similar to that of virgin r...

BACKGROUND Delayed onset of lactogenesis (OL) is most common in primiparas and increases the risk of excess neonatal weight loss, formula supplementation, and early weaning. OBJECTIVE We examined variables associated with delayed OL among first-time mothers who delivered at term and initiated breastfeeding (n = 431). DESIGN We conducted in-person interviews during pregnancy and at days 0, 3...

The present study demonstrates that ovine placental lactogen (oPL) (ovine chorionic somatotrophin) may have an important role in the mammogenesis and/or lactogenesis of the ewe. Its effects were compared with that already described for ovine growth hormone (oGH). In the first experiment, 40 nulliparous ewes were induced to lactate by means of a 7 day (days 1-7) oestro-progestative treatment (E2...

Charoenphandhu N, Nakkrasae L, Kraidith K, Teerapornpuntakit J, Thongchote K, Thongon N, Krishnamra N. Two-step stimulation of intestinal Ca absorption during lactation by longterm prolactin exposure and suckling-induced prolactin surge. Am J Physiol Endocrinol Metab 297: E609–E619, 2009. First published June 30, 2009; doi:10.1152/ajpendo.00347.2009.—During pregnancy and lactation, the enhanced...

Analizar la relación del retraso de lactogénesis II con percepción materna leche insuficiente. Se realizó un estudio observacional longitudinal prospectivo, multicéntrico. obtuvieron datos al alta y entre 1 5 meses posparto sobre insuficiente las variables relacionadas mediante cuestionario autoadministrado el posterior seguimiento postal online. Para desarrollo modelo explicativo, se análisis ...