نتایج جستجو برای: keywords adipose tissue

تعداد نتایج: 2880007  

Journal: :The Journal of Physiology 1945

Journal: :Nature Immunology 2018

2016
Gita Krievina Peteris Tretjakovs Ilze Skuja Vija Silina Laura Keisa Daiga Krievina Guntis Bahs

OBJECTIVE A potential mechanism by which obesity could promote hypertension and kidney diseases is through accumulation of adipose tissue in the renal sinus (RS). The aim of the study was to quantify RS and abdominal adipose tissue volumes and to evaluate serum kidney injury molecule (sKIM)-1 and fibroblast growth factor (FGF)-21 association with different adipose tissue compartments. METHODS...

2010
Olga Gealekman Juerg Straubhaar Richard A. Perugini Silvia Corvera

Background—Adipose tissue expands in response to excess caloric intake, but individuals prone to deposit visceral instead of subcutaneous adipose tissue have higher risk of metabolic disease. The role of angiogenesis in the expandability of human adipose tissue depots is unknown. The objective of this study was to measure angiogenesis in visceral and subcutaneous adipose tissue and to establish...

Journal: :Diabetes 2008
Séverine Ledoux Isabelle Queguiner Simon Msika Sophie Calderari Pierre Rufat Jean-Marie Gasc Pierre Corvol Etienne Larger

OBJECTIVE The expansion of adipose tissue is linked to the development of its vasculature. However, the regulation of adipose tissue angiogenesis in humans has not been extensively studied. Our aim was to compare the angiogenesis associated with subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) from the same obese patients in an in vivo model. RESEARCH DESIGN AND METHODS Adi...

Journal: :Circulation 2011
Olga Gealekman Nina Guseva Celia Hartigan Sarah Apotheker Matthew Gorgoglione Kunal Gurav Khan-Van Tran Juerg Straubhaar Sarah Nicoloro Michael P Czech Michael Thompson Richard A Perugini Silvia Corvera

BACKGROUND Adipose tissue expands in response to excess caloric intake, but individuals prone to deposit visceral instead of subcutaneous adipose tissue have higher risk of metabolic disease. The role of angiogenesis in the expandability of human adipose tissue depots is unknown. The objective of this study was to measure angiogenesis in visceral and subcutaneous adipose tissue and to establish...

Journal: :Journal of animal science 2006
G J Hausman S P Poulos R L Richardson C R Barb T Andacht H C Kirk R L Mynatt

Although microarray and proteomic studies have indicated the expression of unique and unexpected genes and their products in human and rodent adipose tissue, similar studies of meat animal adipose tissue have not been reported. Thus, total RNA was isolated from stromal-vascular (S-V) cell cultures (n = 4; 2 arrays; 2 cultures/array) from 90-d (79% of gestation) fetuses and adipose tissue from 1...

Journal: :Clinical and translational discovery 2022

Glucose and lipids are important nutrients because they provide enough energy for cell activity. However, the human body takes in too much glucose lipids, will cause obesity, diabetes some other metabolism diseases. Adipose tissue exerts crucial roles regulating whole-body metabolic through its storage secretion function. Exosomes a family of extracellular vesicles released by all types that ai...

Journal: :Experimental Gerontology 2016
Allyson K. Palmer James L. Kirkland

Adipose tissue dysfunction occurs with aging and has systemic effects, including peripheral insulin resistance, ectopic lipid deposition, and inflammation. Fundamental aging mechanisms, including cellular senescence and progenitor cell dysfunction, occur in adipose tissue with aging and may serve as potential therapeutic targets in age-related disease. In this review, we examine the role of adi...

Journal: :Tissue Engineering Part B: Reviews 2010

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