PURPOSE To investigate blood creatinine and renal histology in rats anesthetized with S(+)-ketamine (keta) or dexmedetomidine (dex) and submitted to kidney ischemia/reperfusion injury (IRI). METHODS Under intraperitoneal (ip) S(+)-ketamine, 20 male Wistar rats were divided into two groups (n=10): maintenance with iv S(+)-ketamine or dex (keta and dex groups), and submitted to right (R) nephre...

provided the original work is properly cited. CC Intravenous patient-controlled analgesia (IV-PCA) using opioids allows the patient to control the amount of analgesic according to the degree of pain. For effective pain reduction and avoidance of opioid-related complications, studies have investigated methods of combining opioid use with drugs such as NSAIDs, ketamine, clonidine, and dexmedetomi...

There is a scarcity of information for reliable and safe protocol semen collection in R. timorensis. The induction general anesthesia by Ketamine-Xylazine both intravenous intramuscular routes provides valuable the practicality procedure. Five healthy matured Rusa timorensisstags, aged more than 3 years, weighing an average 68.5 ± 2.4 kg were selected this experiment. General anaesthesia was co...

Background Chronic postsurgical pain can severely impair patient health and quality of life. This systematic review update evaluated the effectiveness systemic drugs to prevent chronic pain. Methods The authors included double-blind, placebo-controlled, randomized controlled trials including adults that perioperative drugs. Studies same drug(s) administered similarly were pooled. primary outcom...

OBJECTIVES Low-dose ketamine has been used perioperatively for pain control and may be a useful adjunct to intravenous (IV) opioids in the control of acute pain in the emergency department (ED). The aim of this study was to determine the effectiveness of low-dose ketamine as an adjunct to morphine versus standard care with morphine alone for the treatment of acute moderate to severe pain among ...

BACKGROUND This study investigated the antinociceptive effects of a constant rate infusion (CRI) of lidocaine during xylazine and ketamine anesthesia in horses and aimed to correlate these effects with cardiorespiratory variables, bispectral index (BIS) and plasma lidocaine concentrations. Six adult crossbred mares weighing 320-400 kg were anesthetized on three different occasions. Sedation was...

The objective of this study was to compare 3 total intravenous anesthetic infusion combinations in adult horses for cardiopulmonary changes, muscle relaxation, duration of recumbency, and quality of recovery. This was a prospective, randomized, crossover, experimental study. Six healthy, adult, mixed-breed horses weighing 460 ± 30 kg were used. The 3 total intravenous anesthetic combinations us...

Background: High blood sugar is a typical reaction to stress. In the diabetic population, hyperglycemia can be serious issue and has been linked higher mortality rates. Recent studies have shown that anesthetics reduced glucose tolerance; however, it still unclear how propofol, ketamine, thiopental of Na affect metabolism. The present study compared levels Na, propofol among patients with catar...

The Ketamine Stun is simply the addition of a small dose of ketamine to any injectable chemical restraint technique. I initially developed the Ketamine Stun technique in the early 1990's to cover my limited cat handling abilities. My first exposure to camelid patients came when I left equine practice to teach at Ohio State. The recalcitrant behavior they frequently exhibited quickly led to expe...