Uveal melanoma, which is the most common primary intraocular malignancy in adults, arises from melanocytes within the iris, ciliary body and choroid. The diagnosis is based principally on clinical examination of the tumor with biomicroscopy and indirect ophthalmoscopy and confirmed by diagnostic techniques such as ultrasonography, fundus fluorescein angiography and optical coherence tomography....

BACKGROUND Scleritis may be the initial or only presenting feature of systemic, autoimmune, or infectious disorders. Corticosteroids are the mainstay of treatment for immune-mediated scleritis. However, steroids could prove detrimental when used to treat infectious scleritis. Hence, infectious causes of scleritis should be ruled out. FINDINGS A 47-year-old male from central India presented wi...

purpose : to compare intraocular pressure (iop) readings measured by the ocular response analyzer (ora) with those measured by the goldmann applanation tonometer (gat) in keratoconic eyes following penetrating keratoplasty (pkp) and evaluate the influence of anatomical and biomechanical properties of the grafts on the iop measurements methods : in this cross-sectional study conducted on 45 kera...

The retinoblastomais known as the most common intraocular malignancy of the childhood. In addition to other diagnostic methods theOptical Coherence Tomography (OCT) may be considered an important tool in the evaluation ofselective involvement of the retinaby small and medium sized tumors at the posterior pole of the eye.The authors present two cases of retinoblastoma in which the OCT was ableto...

Choroidal osteoma is a rare benign intraocular tumor composed of calcification throughout the choroid. Various treatment modalities are available according to location of the tumor and the cause of the visual distortion. We report herein a 30-year-old male who was referred to our hospital with acute blurred vision as a result of the subretinal hemorrhage from choroidal osteoma. We ruled out the...

Understanding the mechanism of retinoblastoma (Rb) tumor initiation, development, progression and metastasis in vivo mandates the use of animal models that mimic this intraocular tumor in its genetic, anatomic, histologic and ultrastructural features. An early setback for developing mouse Rb models was that Rb mutations did not cause tumorigenesis in murine retinas. Subsequently, the discovery ...

Photodynamic therapy (PDT) has been used for treatment of various intraocular tumors including choroidal hemangioma, vasoproliferative tumor, amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma. This case report documents the effect of PDT for a presumed acquired retinal astrocytoma. A 42-year-old female with a juxtapapillary acquired astrocytoma was treate...

Application of knowledge discovery in databases (data mining) for medical decision support is discussed in this work. The aim of the study was to use decision support algorithm for the differential diagnosis of intraocular tumors using parameters from eye images obtained by the ultrasound examination. Application of predictive modeling algorithm for decision tree formation using See5.0/C5.0 dat...

purpose: to report a case of unilateral severe visual loss and bilateral optic disc cupping secondary to brain metastasis of bronchogenic carcinoma patient and findings: a 48 year-old woman presented with severe visual loss of left eye without redness or pain or any systemic findings .clinical findings included decreased visual acuity of left eye to 4 m cf and (+3) positive marcus-gunn reflex ....

purpose: to report a rare case of ciliochoroidal malignant melanoma presenting as a subconjunctival black-colored mass adjacent to the limbus. patient and findings: a 42-year-old woman presented with a subconjunctival black-colored mass adjacent to the limbus in left eye from 2 years ago. the lesion had increased in size during the previous 2 months. funduscopic examination with scleral depress...