It is known that marijuana smoking and administration of natural cannabinoids reduce intraocular pressure. However, it has not been established whether the intraocular pressure-lowering effects of cannabinoids are mediated by cannabinoid receptors. Aminoalkylindoles are a new class of cannabimimetics with structures entirely different from those of natural cannabinoids. WIN55212-2, a prototypic...

The parallel, randomized, double-masked, activecontrolled trial is generally thought to be the most rigorous and unbiased design to adequately compare two glaucoma medicines. Important to this design is the intraocular pressure entry criteria. The lower limit of intraocular pressure is usually set at least >21 mmHg to help assure the study population has the appropriate diagnosis (ocular hypert...

Uveal melanoma (UM) is the most frequent intraocular malignancy in adults, affecting iris, choroid, and ciliary bodies [...]

Cutaneous tuberculosis (cTB) represents 1-2% of extrapulmonary [1] and is caused by the Mycobacterium tuberculosis complex (M. tuberculosis, M. bovis, africanum, microti, canetti, caprae, pinnipedii).

Background: Peritoneal tuberculosis accounts 1-2% of all forms of tuberculosis. Peritoneal tuberculosis is an important differential diagnosis for ovarian cancer in women with ascites, adnexal mass and elevated cancer antigen 125 (CA125) levels. We report a case of a 32- year -old woman with multiple miliary peritoneal deposits mimicking advanced ovarian carcinoma. Case Presentation: A 32-ye...

AIMS To investigate the effect of central corneal thickness and corneal curvature on intraocular pressure measurements using the pulsatile ocular blood flow tonograph and the Goldmann applanation tonometer, and to assess the agreement between the pulsatile ocular blood flow tonograph and the Goldmann applanation tonometer in intraocular pressure measurement. METHODS 479 subjects underwent int...

Tuberculosis and smoking are among the most pressing issues in modern health care system world. patients who smoke confirmed to have reduced effectiveness of anti-tuberculosis therapy, unsatisfactory prognosis a specific disease, higher risk treatment failure mortality from this disease. Diseases such as HIV alcoholism increase ineffective tobacco smokers. In addition, leads increased virulence...

Background & Objective: Mutations in embB306 gene and their association with resistance to ethambutol (EMB) in Mycobacterium tuberculosis (M. tuberculosis) have not been fully investigated. The aim of this study was to investigate the point-mutations in emb306B gene and their association with resistance to EMB in M. tuberculosis. Materials & Methods: This case (M. tuberculosis resistant to EMB...