ABSTRACT Introduction: Frequency of Tramadol intoxication is increasing as a result of its use as a drug for suppression of withdrawal symptoms by opioids abusers and its wide accessibility of this drug. Tramadol intoxication can lead to death and, therefore, early identification of its clinical manifestations is crucial since early detection of the intoxication and its treatment could impro...

Alcohol addiction and intoxication are major health problems worldwide. Acute alcohol intoxication is well reported in adults and adolescents but less frequently reported in children of younger ages. We report three anonymized cases of pediatric ethanol exposure and illustrate the different mechanisms of intoxication. In all cases, a focused history is the key to prompt diagnosis and timely man...

Background: Unintentional drug intoxication is still a major cause of mortality and morbidity in young children. Method & Materials: In order to study changes of epidemiological indices of children intoxication during a 10-year period in Hamadan Province, all cases admitted to Ghaem Hospital from 1995-1999 were recruited, and compared with all cases admitted to the same hospital from 1990-1...

Abstract Background The urine immunochromatographic assay is a useful screening tool for patients suspected of acute drug intoxication in emergency conditions. Diphenhydramine shows symptoms similar to those tricyclic antidepressant (TCA) intoxication. Case presentation We examined case diphenhydramine showing cerebellar ataxia and prolonged false positive results TCA the urine. test showed per...

BACKGROUND Organophosphates are frequently used as insecticides in the household and in agricultural areas, thus posing a risk for accidental exposure. OBJECTIVES To describe the characteristics, clinical course and outcome of 97 patients admitted to emergency rooms with a diagnosis of acute OP poisoning. METHODS The clinical details of 97 patients were collected from 6 different hospitals ...

The combined use of hepatoprotectors and phytosorbents in theory is a promising method pharmacotherapy comorbid pathologies, as it creates the possibility presenting them result an extended search for most relevant forms manifestation metabolic disorders, results which made possible to identify general patterns development and, accordingly, main directions their leveling.It was revealed that pa...

Botulinum neurotoxins (BoNTs) comprise seven distinct serotypes that inhibit the release of neurotransmitter across neuromuscular junctions, resulting in potentially fatal flaccid paralysis. BoNT serotype A (BoNT/A), which targets synaptosomal-associated protein of 25kDa (SNAP-25), is particularly long-lived within neurons and requires a longer time for recovery of neuromuscular function. There...

brain injury associated with methanol toxicity can be ischemic, necrotic or hemorrhagic in nature. it most commonly affects the putamenal area bilaterally, but can be seen in other locations. this report describes a 22-year-old intoxicated patient who developed an epidural hematoma following hemodialysis. heparinization during hemodialysis may contribute to cerebral hemorrhagic complications in...