Tinea corporis is a superficial fungal skin infection of the body caused by dermatophytes. present worldwide. It defined explicitly location lesions that may involve trunk, neck, arms, and legs. Alternative names exist for dermatophyte infections affect other areas body. These include scalp (tinea capitis), face faciei), hands manuum), groin cruris), feet pedis). A case 22 years old male suffer...

Interventions often involve a sequence of decisions. For example, clinicians frequently adapt the intervention to an individual's outcomes. Altering the intensity and type of intervention over time is crucial for many reasons, such as to obtain improvement if the individual is not responding or to reduce costs and burden when intensive treatment is no longer necessary. Adaptive interventions ut...

Malignant bowel obstruction requires a highly individualized approach, tailored to the patient's medical condition, prognosis, and goals of care. Surgery should not be routinely done. Less-invasive approaches such as gastric and colonic stenting are useful.

IntroductIon Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective death of upper motor neurons (UMNs) and lower motor neurons (LMNs), typically may die from respiratory failure within 2–5 years of symptom onset.[1] About 10% of ALS patients are familial whereas the remaining patients are sporadic. ALS is highly heterogeneous in genetic and cl...

Clinical studies model the average treatment effect (ATE), but apply this population-level effect to future individuals. Due to recent developments of machine learning algorithms with useful statistical guarantees, we argue instead for modeling the individualized treatment effect (ITE), which has better applicability to new patients. We compare ATE-estimation using randomized and observational ...