Diversity among the pathogenic strains of Theileria equi (T. equi), a major agent of equine piroplasmosis, can affect the appropriate detection of parasite and host immunization. Production of recombinant surface proteins from an infected horse in natural endemic area provides a reliable tool for immunodiagnosis of parasite. Regarding this, the present study was targeted toward the cloning, exp...

Periodontitis is a frequent chronic inflammatory disorder destroying periodontium. Recent studies have revealed the role of bromodomain and extraterminal domain inhibitor (BETi) microRNA (miR)-130a in regulating macrophage polarization pro-inflammatory response. However, little known about whether apabetalone (a novel BETi) miR-130a are correlated with state periodontitis by polarization. Here ...

Introduction: In immuno-electron microscopy, electron-dense labels are required to permit localisation of the bound antibody molecules. One of the most successful is ferritin [1-3]. If conjugated antibody is present in the immunolabelling mixture, it must have the effect of diminishing sensitivity, perhaps critically, by competing for the antigenic sites. Therefore, it is important to remove fr...

1.Blum, H., H. Beier, and H.J. Gross. 1987. Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels. Electrophoresis 8:93-99. 2.Görg, A., G. Boguth, C. Obermaier, A. Posch, and W. Weiss. 1995. Two-dimensional polyacrylamide gel electrophoresis with immobilized pH gradients in the first dimension (IPG-Dalt): the state of the art and the controversy of vertical versus horiz...

hydatidosis is a disease caused by infection with the metacestode stage of the dog tapeworm,echinococcus granulosus. this is recognised as one of the world’s most important zoonoses, affecting bothhumans and their domestic animals. in the current study, 20 sheep cystic livers or lungs were collected.hydatid fluid and protoscolices were isolated and the soluble protein was prepared. polypeptide ...

Snake venom is a complex mixture of proteins, peptides, enzymes, carbohydrates, and minerals. They contain a variety of chemicals with pharmacological and toxicological properties. The innate immune system is the first line of defense against toxins and microbes. Antibacterial and anticancer proteins produced by snake venom have recently attracted significant attention due to their relevance to...

cystic fibrosis is an autosomal recessive disease caused by a wide spectrum of mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator protein. these mutations that correlate with different phenotypes, vary in their frequency and distribution in different populations. in this study missense mutation r117h that associated with the different clinical symptoms wa...