Objective: The present study was designed to investigate the putative antidepressant effects of crocin and crocetin, two major active ingredients of Crocus sativus L. (saffron) using mice in two different regimens of acute and sub-acute administration. Material and Methods: In acute treatment, antidepressant-like activities of crocin and crocetin (10, 20 and 40 mg/kg, i.p.) were evaluated using...

Introduction: In this study the antidepressant effect of a new morpholino betalactam composition, 1-(3- morpholinopropyl)-4-(naphthalene-2-yl)-3-phenoxyazetidin-2-one (EB9) administered at three doses, was investigated in an animal model of depression. The CNS stimulant, muscle coordination and toxic effects of this compound were also tested. Methods: Morpholino betalactam at 10, 15 and 20 ...

Objective: Caryophyllus aromaticus mill L (Caryophyllus aromaticus) is a herbal spice plant that has several therapeutic effects. It also heals depression, grief, nervous stress and tension. In the present study we evaluated antidepressant-like effect of Caryophyllus aromaticus using forced swimming test (FST). Material and Methods: Three doses of ethanolic extract (50, 100 and 200 mg/kg) was i...

Tonic immobility reaction and heterophil:lymphocyte ratio were studied in hens laying pink eggs from three brown egg Spanish breeds (Barred Red Vasca, Red Vasca, Red Villafranquina). There was no significant difference among breeds in terms of tonic immobility duration or heterophil:lymphocyte ratio. Tonic immobility duration was significantly shorter in the pink (220 + or - 23 s) than in the n...

WooKiEum (WKE) has been used for the purpose of the development of increased immune-system strength in Korea. In the present study, we examined the anti-immobility effect of WKE on the forced swimming test (FST), and then measured blood biochemical parameters related to fatigue: glucose (Glc), blood urea nitrogen (BUN), lactic dehydrogenase (LDH), creatinine, and total protein (TP). WKE (0.1, 1...

Objective: Rosa damascena mill L (R. damascena) is a medicinal plant mostly known in the world for its perfume. It also has beneficial effects on stress, tension and depression. In this experiment antidepressant effect of ethanolic extract of R. damascena by forced swimming test (FST) was evaluated. Material and Methods: Animals received ethanolic extract (15, 60 and 90 mg/kg, i.p), imipramine ...

Discussions on transit migration have for long focused presenting the experiences of migrants transiting through a given place at specific time in linear manner. Accordingly, most prior researches adopt snapshot approach to examine lived experience migrants. This paper argues that such an fails aptly capture gist complex nature and dynamics change trajectories. It emphasizes need diachronic exa...