hypertension crisis is one of the main health problems and its effective treatment is of high importance. for this purpose, fast-disintegrating and sustained release formulations of captopril, as a drug of choice, were prepared using conventional mucoadhesive polymers hydroxypropyl methylcellulose (hpmc), sodium carboxymethyl cellulose (na-cmc), hydroxypropyl cellulose (hpc), carbopol 934 (cp93...

Front Cover: In article number 2100383, Ana-Maria Resmerita and co-workers show that incorporation of 5 wt% polystyrene/hydroxypropyl-β-cyclodextrins (HPβCD) semi-rotaxane into a polyethylene glycol/HPβCD crosslinked matrix leads to hydrophobic porous film with enhanced swelling ability thermal dielectric properties as compared those the pure material.

Objectives Failure to publish findings from research is a significant area of research waste. It has previously been suggested that potentially over 50% of studies funded are never published. This study aimed to investigate what percentage of NIHR HTA programme funded projects have published their final reports in the programme’s journal Health Technology Assessment, (the monograph series); and...

BACKGROUND Decision-analytic modelling (DAM) has become a widespread method in health technology assessments (HTA), but the extent to which modelling is used differs among international HTA institutions. In Germany, the use of DAM is optional within HTAs of the German Institute of Medical Documentation and Information (DIMDI). Our study examines the use of DAM in DIMDI HTA reports and its effec...